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Hypothyroidism — Treatment Landscape & Competitive Intelligence
7 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| Synthroid | levothyroxine | Generic (originally multiple — AbbVie/Synthroid) | Thyroid hormone | THAP domain-containing protein 1, Macrophage migration inhibitory factor, Malate dehydrogenase, mitochondrial | 2002-08-13 | |
| Unithroid | LEVOTHYROXINE SODIUM | Fresenius Kabi | l-Thyroxine | Thyroid hormone receptor beta | 2000-01-01 | |
| Triostat | LIOTHYRONINE | Pfizer | l-Triiodothyronine | Thyroid hormone receptor alpha | 1956-01-01 | |
| Triiodothyronine | Triiodothyronine | Northwell Health | THAP domain-containing protein 1, Cytochrome P450 2C9, Proliferating cell nuclear antigen | |||
| Thyroxine | Thyroxine | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | THAP domain-containing protein 1, Macrophage migration inhibitory factor, Malate dehydrogenase, mitochondrial | |||
| levothyroxin | levothyroxin | Ain Shams University | THAP domain-containing protein 1, Macrophage migration inhibitory factor, Malate dehydrogenase, mitochondrial | |||
| Cytomel | Liothyronine Sodium | Pfizer Inc. | Thyroid hormone replacement | Thyroid receptor proteins attached to DNA |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- Ain Shams University · 1 drug in Hypothyroidism
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences · 1 drug in Hypothyroidism
- Fresenius Kabi · 1 drug in Hypothyroidism
- Generic (originally multiple — AbbVie/Synthroid) · 1 drug in Hypothyroidism
- Northwell Health · 1 drug in Hypothyroidism
- Pfizer · 1 drug in Hypothyroidism
- Pfizer Inc. · 1 drug in Hypothyroidism
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Cite this brief
Drug Landscape (2026). Hypothyroidism — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/hypothyroidism. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing