Last reviewed · How we verify
Thyroxine
At a glance
| Generic name | Thyroxine |
|---|---|
| Also known as | levothyroxine, T4, Euthyrox, Carbimazole, Levothyroxine |
| Sponsor | Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
| Target | THAP domain-containing protein 1, Macrophage migration inhibitory factor, Malate dehydrogenase, mitochondrial |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | FDA-approved |
Approved indications
- Congenital hypothyroidism
- Diagnostic Test for Thyroid Dysfunction
- Goiter
- Hashimoto thyroiditis
- Hyperlipidemia
- Hypothyroidism
- Malignant tumor of thyroid gland
- Myxedema
Common side effects
Key clinical trials
- A Randomised, Controlled, Crossover Study: Treatment With Thyroxin Compared to Thyroxin + Triiodothyronin in Patients With Secondary Hypothyroidism (Phase 4)
- The Observation Study of Graves' Disease Cohort (N/A)
- Are IQs Low in Offspring of Euthyroid Women With Low T4? (N/A)
- Targeted Levothyroxine Dosing in Infants With Congenital Hypothyroidism (NA)
- MASLD in Primary Hypothyroidism and Efficacy of Dapaglifozin (EARLY/Phase 1)
- Congenital Hypothyroidism in Children With Eutopic Gland or Thyroid Hemiagenesis: Predictive Factors for Transient vs Permanent Hypothyroidism. (N/A)
- Thyroid Hormone Dose Adjustments During Pregnancy in Women With Primary Hypothyroidism. (NA)
- Is There a Role for Thyroid Hormones Treatment in the Set-up of Acute Moderate to Severe Asthma Exacerbation (NA)
Primary sources
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| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |