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Fever — Treatment Landscape & Competitive Intelligence

Fever (disease) competitive landscape: 10 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

10 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Fever, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Aleve naproxen Generic (originally Syntex) NSAID Aldo-keto reductase family 1 member C2, Aldo-keto reductase family 1 member C3, Prostaglandin G/H synthase 1 1976-01-01
Sudafed PE phenylephrine Generic (multiple manufacturers) Alpha-1 adrenergic agonist (decongestant/vasopressor) Alpha-1A adrenergic receptor, Alpha-1B adrenergic receptor, Alpha-1D adrenergic receptor 1976-01-01
Immune Support CORTISONE Merck Non-Standardized Plant Allergenic Extract [EPC] 1974-01-01
Lithobid lithium carbonate Generic (multiple manufacturers) Mood stabilizer Inositol-1(or 4)-monophosphatase 1, Glycogen synthase kinase-3 1970-04-06
Advil ibuprofen Generic (originally Boots Group) Nonsteroidal Anti-inflammatory Drug [EPC] Sodium-coupled monocarboxylate transporter 1, Acid-sensing ion channel 1, Aldo-keto reductase family 1 member C2 1969-01-15
Acetaminophen Paracetamol Polymedica acetaminophen Transient receptor potential cation channel subfamily V member 4 1968-01-01
Delsym dextromethorphan Generic (originally Roche) Antitussive (non-opioid) Taste receptor type 2 member 46, Solute carrier family 22 member 1, Cytochrome P450 2D6 1958-01-01
Mucinex guaifenesin Generic (multiple manufacturers) Expectorant [EPC] Vagal gastric reflex → increased respiratory secretions 1952-01-01
Phenergan Vc W/ Codeine PHENYLEPHRINE BITARTRATE ANI Pharmaceuticals Nonsteroidal Anti-inflammatory Drug [EPC] Alpha-1B adrenergic receptor 1952-01-01
Codeine codeine phosphate Generic (multiple manufacturers) Opioid analgesic, Antitussive Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor 1950-01-01

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Generic (multiple manufacturers) · 4 drugs in Fever
  2. · 4 drugs in Fever
  3. Generic (originally Boots Group) · 1 drug in Fever
  4. Generic (originally Roche) · 1 drug in Fever
  5. Generic (originally Syntex) · 1 drug in Fever
  6. HF Acquisition Co LLC, DBA HealthFirst · 1 drug in Fever
  7. Merck · 1 drug in Fever
  8. Pfizer · 1 drug in Fever
  9. Polymedica · 1 drug in Fever
  10. ANI Pharmaceuticals · 1 drug in Fever

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Cite this brief

Drug Landscape (2026). Fever — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/fever. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing