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Erosive esophagitis — Treatment Landscape & Competitive Intelligence
10 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| Dexilant | DEXLANSOPRAZOLE | Takeda | Proton Pump Inhibitor [EPC] | (H+, K+)-ATPase | 2009-01-01 | |
| Nexium | esomeprazole | AstraZeneca | Proton pump inhibitor (PPI) | Potassium-transporting ATPase | 2001-02-20 | |
| Protonix | pantoprazole | Generic (originally Byk Gulden/Altana/Nycomed) | Proton pump inhibitor (PPI) | ATP-binding cassette sub-family G member 2, Fatty acid synthase, Multidrug and toxin extrusion protein 1 | 2000-02-02 | |
| Pantoprazole Sodium | Pantoprazole Sodium | Pfizer | Proton pump inhibitor (PPI) | (H+, K+)-ATPase enzyme | 2000-01-01 | |
| Prevacid | lansoprazole | Generic (originally Takeda) | Proton pump inhibitor (PPI) | ATP-binding cassette sub-family G member 2, Cytochrome P450 2C19, Cytosolic endo-beta-N-acetylglucosaminidase | 1995-05-10 | |
| Prilosec | omeprazole | AstraZeneca (originally Astra AB) | Proton pump inhibitor (PPI) | ATP-binding cassette sub-family G member 2, Cytochrome P450 1A2, Cytochrome P450 2C19 | 1989-09-14 | |
| Pepcid | famotidine | Generic (originally Yamanouchi/Merck) | Histamine-2 Receptor Antagonist [EPC] | Multidrug and toxin extrusion protein 1, Multidrug and toxin extrusion protein 2, Solute carrier family 22 member 2 | 1986-10-01 | |
| Zantac | ranitidine | GSK (originally Glaxo) | H2 receptor antagonist | Multidrug and toxin extrusion protein 1, Acetylcholinesterase, Histamine H2 receptor | 1983-06-01 | |
| Dexilant | Dexilant | Genuine Research Center, Egypt | Sterile alpha and TIR motif-containing protein 1, Cytosolic endo-beta-N-acetylglucosaminidase, Potassium-transporting ATPase | |||
| Rabeprazole 40 mg | rabeprazole-40-mg | Pfizer | Proton Pump Inhibitor | H+/K+ ATPase |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
- — Pepcid · FDA · approved · US
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- Pfizer · 2 drugs in Erosive esophagitis
- · 2 drugs in Erosive esophagitis
- AstraZeneca (originally Astra AB) · 1 drug in Erosive esophagitis
- Chang Gung Memorial Hospital · 1 drug in Erosive esophagitis
- GSK (originally Glaxo) · 1 drug in Erosive esophagitis
- Generic (originally Byk Gulden/Altana/Nycomed) · 1 drug in Erosive esophagitis
- Generic (originally Takeda) · 1 drug in Erosive esophagitis
- Generic (originally Yamanouchi/Merck) · 1 drug in Erosive esophagitis
- Genuine Research Center, Egypt · 1 drug in Erosive esophagitis
- Northern Orthopaedic Division, Denmark · 1 drug in Erosive esophagitis
- RenJi Hospital · 1 drug in Erosive esophagitis
- Takeda · 1 drug in Erosive esophagitis
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Cite this brief
Drug Landscape (2026). Erosive esophagitis — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/erosive-esophagitis. Accessed 2026-06-10.
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