Last reviewed 2026-04-19 · How we verify

Erosive esophagitis

16 treatments

Approved treatments

Dexpure
Dexpure works by irreversibly inhibiting the H+/K+ ATPase enzyme in the stomach lining, reducing acid production.
Dexilant · Takeda
Dexlansoprazole inhibits gastric acid secretion by blocking the (H+, K+)-ATPase enzyme, known as the proton pump, in gastric parietal cells.
Zantac · GSK (originally Glaxo)
Dexlan · Chang Gung Memorial Hospital
Pepcid · Generic (originally Yamanouchi/Merck)
Competitively blocks histamine H2 receptors on gastric parietal cells, reducing basal and stimulated acid secretion.
Dexilant · Genuine Research Center, Egypt
Prevacid · Vanderbilt University Medical Center
Nexium · AstraZeneca
Protonix · Generic (originally Byk Gulden/Altana/Nycomed)
Irreversibly inhibits the gastric proton pump (H+/K+ ATPase), suppressing stomach acid secretion.
Pantoprazole Sodium · Pfizer
Pantoprazole suppresses gastric acid by covalently binding the (H+, K+)-ATPase enzyme at parietal cells.
Prilosec · AstraZeneca (originally Astra AB)
Irreversibly inhibits the hydrogen-potassium ATPase (proton pump) in gastric parietal cells, potently suppressing stomach acid secretion.
Rabeprazole 40 mg · Pfizer
Axid Ar
Omeprazol · RenJi Hospital
Pantoprazol · Northern Orthopaedic Division, Denmark
Prevacid · Generic (originally Takeda)
Irreversibly inhibits the gastric proton pump to suppress acid secretion.

Clinical guidelines

FDA label — 1L
Pantoprazole Sodium for Injection is indicated for the treatment of gastroesophageal reflux disease (GERD) and a history of erosive esophagitis (EE) for up to 10 days in adults.
FDA label — 1L
Pantoprazole Sodium for Injection is indicated for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome in adults.
FDA label — 1L
Pantoprazole Sodium for Injection is indicated for the treatment of gastroesophageal reflux disease (GERD) and a history of erosive esophagitis (EE) for up to 10 days in adults.
FDA label — maintenance
Pantoprazole Sodium for Injection is indicated for the maintenance of healing of erosive esophagitis.
FDA label — 1L
Pantoprazole Sodium for Injection is indicated for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome in adults.
FDA label — 1L
Omeprazole is used to treat erosive esophagitis.
FDA label — maintenance
Pantoprazole Sodium for Injection is indicated for the maintenance of healing of erosive esophagitis.
FDA label — 1L
Pantoprazole Sodium for Injection is indicated for the treatment of gastroesophageal reflux disease (GERD) and a history of erosive esophagitis (EE) for up to 10 days in adults.
FDA label — 1L
Pantoprazole Sodium for Injection is indicated for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome in adults.
FDA label — 1L
Pantoprazole Sodium for Injection is indicated for the treatment of gastroesophageal reflux disease (GERD) and a history of erosive esophagitis (EE) for up to 10 days in adults.
FDA label — 1L
Pantoprazole Sodium for Injection is indicated for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome in adults.

Competitive intelligence

For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:

Erosive esophagitis patent landscape — cliff calendar, originator estates, attackable patents
Erosive esophagitis treatment landscape brief
Erosive esophagitis treatment updates RSS

Frequently asked questions about Erosive esophagitis

What drugs treat Erosive esophagitis?

Tracked treatments include Dexpure, Dexilant, Zantac, Dexlan, Pepcid, Prevacid, Nexium, Protonix.

What is the treatment for Erosive esophagitis?

Standard treatment for Erosive esophagitis includes Dexpure, Dexilant, Zantac, Dexlan, Pepcid. See the treatment landscape page for first-line, second-line and salvage options.

What are the treatment guidelines for Erosive esophagitis?

FDA label publishes guidelines for Erosive esophagitis. 11 guideline references tracked.

Treatment landscape: Erosive esophagitis patent cliff · Erosive esophagitis CI report
Treatment: Dexpure
Treatment: Dexilant · Takeda
Treatment: Zantac · GSK (originally Glaxo)
Treatment: Dexlan · Chang Gung Memorial Hospital
Treatment: Pepcid · Generic (originally Yamanouchi/Merck)
All diseases: Browse the disease index · Disease landscape hub

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing