How many drugs treat Edema due to Nephrotic Syndrome?

Drug Landscape tracks 5 marketed treatments for Edema due to Nephrotic Syndrome (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

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Last reviewed 2026-06-10 · How we verify

Edema due to Nephrotic Syndrome — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Edema due to Nephrotic Syndrome (disease) competitive landscape: 5 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

5 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Edema due to Nephrotic Syndrome, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Aldactone	spironolactone	Generic (originally Searle/Pfizer)	Aldosterone Antagonist [EPC]	Cytochrome P450 2C19, Multidrug and toxin extrusion protein 1, Nuclear receptor subfamily 1 group I member 2	1960-01-01
Microzide	hydrochlorothiazide	Generic (originally Merck)	Thiazide Diuretic [EPC]	ACE	1959-01-01
Diuril	CHLOROTHIAZIDE	Salix Pharms	Thiazide Diuretic	Solute carrier family 12 member 3	1958-01-01
Spironolacton	Spironolacton	ACS Biomarker		Cytochrome P450 2C19, Multidrug and toxin extrusion protein 1, Nuclear receptor subfamily 1 group I member 2
spirolactone	spirolactone	Second Xiangya Hospital of Central South University		Cytochrome P450 2C19, Multidrug and toxin extrusion protein 1, Nuclear receptor subfamily 1 group I member 2

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

ACS Biomarker · 1 drug in Edema due to Nephrotic Syndrome
Generic (originally Merck) · 1 drug in Edema due to Nephrotic Syndrome
Generic (originally Searle/Pfizer) · 1 drug in Edema due to Nephrotic Syndrome
Salix Pharms · 1 drug in Edema due to Nephrotic Syndrome
Second Xiangya Hospital of Central South University · 1 drug in Edema due to Nephrotic Syndrome

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Every new regulatory action, PDUFA date, or trial completion in Edema due to Nephrotic Syndrome:

Cite this brief

Drug Landscape (2026). Edema due to Nephrotic Syndrome — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/edema-due-to-nephrotic-syndrome. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing