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Duodenal ulcer disease — Treatment Landscape & Competitive Intelligence

Duodenal ulcer disease (disease) competitive landscape: 10 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

10 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Duodenal ulcer disease, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Aciphex rabeprazole Waylis Proton Pump Inhibitor Potassium-transporting ATPase 1999-01-01
Prevacid lansoprazole Generic (originally Takeda) Proton pump inhibitor (PPI) ATP-binding cassette sub-family G member 2, Cytochrome P450 2C19, Cytosolic endo-beta-N-acetylglucosaminidase 1995-05-10
Prilosec omeprazole AstraZeneca (originally Astra AB) Proton pump inhibitor (PPI) ATP-binding cassette sub-family G member 2, Cytochrome P450 1A2, Cytochrome P450 2C19 1989-09-14
Pepcid famotidine Generic (originally Yamanouchi/Merck) Histamine-2 Receptor Antagonist [EPC] Multidrug and toxin extrusion protein 1, Multidrug and toxin extrusion protein 2, Solute carrier family 22 member 2 1986-10-01
Zantac ranitidine GSK (originally Glaxo) H2 receptor antagonist Multidrug and toxin extrusion protein 1, Acetylcholinesterase, Histamine H2 receptor 1983-06-01
Gaviscon ALGELDRATE Sanofi algeldrate 1983-01-01
Carafate sucralfate Generic (originally Marion Merrell Dow) Aluminum Complex [EPC] Pepsin A-5 1981-10-30
Carafate Carafate Forest Labs Inc Aluminum Complex [EPC] Pepsin A-5 1981-01-01
Prevacid Prevacid Vanderbilt University Medical Center ATP-binding cassette sub-family G member 2, Cytochrome P450 2C19, Cytosolic endo-beta-N-acetylglucosaminidase
Aciphex Aciphex University of Utah Sterile alpha and TIR motif-containing protein 1, ATP-binding cassette sub-family G member 2, Adenosine receptor A3

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. · 5 drugs in Duodenal ulcer disease
  2. AstraZeneca (originally Astra AB) · 1 drug in Duodenal ulcer disease
  3. Forest Labs Inc · 1 drug in Duodenal ulcer disease
  4. GSK (originally Glaxo) · 1 drug in Duodenal ulcer disease
  5. Generic (originally Marion Merrell Dow) · 1 drug in Duodenal ulcer disease
  6. Generic (originally Takeda) · 1 drug in Duodenal ulcer disease
  7. Generic (originally Yamanouchi/Merck) · 1 drug in Duodenal ulcer disease
  8. Genuine Research Center, Egypt · 1 drug in Duodenal ulcer disease
  9. Janssen-Cilag, S.A. · 1 drug in Duodenal ulcer disease
  10. RenJi Hospital · 1 drug in Duodenal ulcer disease
  11. Sanofi · 1 drug in Duodenal ulcer disease
  12. University of Utah · 1 drug in Duodenal ulcer disease

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Every new regulatory action, PDUFA date, or trial completion in Duodenal ulcer disease:

Cite this brief

Drug Landscape (2026). Duodenal ulcer disease — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/duodenal-ulcer-disease. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing