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Depression Treatment Adjunct — Treatment Landscape & Competitive Intelligence

Depression Treatment Adjunct (disease) competitive landscape: 7 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

7 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Depression Treatment Adjunct, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Abilify aripiprazole Generic (originally Otsuka/BMS) Third-generation antipsychotic (D2 partial agonist) 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6 2002-11-15
Seroquel quetiapine AstraZeneca Aldehyde oxidase, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A
Zyprexa olanzapine Eli Lilly Atypical Antipsychotic [EPC] Aldehyde oxidase, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A
Abilify Abilify Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A, 5-hydroxytryptamine receptor 6
Seroquel Seroquel University of Pittsburgh Aldehyde oxidase, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A
Quetiapin Quetiapin Sykehuset Innlandet HF Aldehyde oxidase, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A
Zyprexa Zyprexa Washington University School of Medicine Aldehyde oxidase, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. AstraZeneca · 1 drug in Depression Treatment Adjunct
  2. Eli Lilly · 1 drug in Depression Treatment Adjunct
  3. Generic (originally Otsuka/BMS) · 1 drug in Depression Treatment Adjunct
  4. Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 1 drug in Depression Treatment Adjunct
  5. Sykehuset Innlandet HF · 1 drug in Depression Treatment Adjunct
  6. University of Pittsburgh · 1 drug in Depression Treatment Adjunct
  7. Washington University School of Medicine · 1 drug in Depression Treatment Adjunct

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Cite this brief

Drug Landscape (2026). Depression Treatment Adjunct — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/depression-treatment-adjunct. Accessed 2026-06-11.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing