Last reviewed · How we verify
Seroquel
At a glance
| Generic name | Seroquel |
|---|---|
| Also known as | Quetiapine, quetiapine, quetiapine XR |
| Sponsor | University of Pittsburgh |
| Target | Aldehyde oxidase, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A |
| Modality | Small molecule |
| Therapeutic area | Neuroscience |
| Phase | FDA-approved |
Approved indications
- Bipolar affective disorder, current episode depression
- Bipolar affective disorder, current episode manic
- Bipolar disorder
- Bipolar disorder in remission
- Depression Treatment Adjunct
- Schizophrenia
Common side effects
- Somnolence
- Dizziness
- Dry mouth
- Constipation
- Weight gain
- ALT increased
- Dyspepsia
- Asthenia
- Abdominal pain
- Postural hypotension
- Pharyngitis
- Lethargy
Serious adverse events
- Hypotension
- Somnolence (discontinuation)
Key clinical trials
- An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine (PHASE4)
- Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure (PHASE3)
- A Study of the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia. (PHASE3)
- Sequential Multiple Assignment Randomized Trial for Bipolar Depression (PHASE4)
- Magnetic Seizure Therapy for Psychotic Disorders (NA)
- National Pregnancy Registry for Psychiatric Medications
- The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. (PHASE3)
- Comparing Antipsychotic Medications in LBD Over Time (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Seroquel CI brief — competitive landscape report
- Seroquel updates RSS · CI watch RSS
- University of Pittsburgh portfolio CI