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Decompensated cardiac failure — Treatment Landscape & Competitive Intelligence
9 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| Natrecor | NESIRITIDE | Scios Llc | Natriuretic Peptide | Atrial natriuretic peptide receptor 1 | 2001-01-01 | |
| Primacor | MILRINONE | Sanofi | Phosphodiesterase 3 Inhibitor | Phosphodiesterase 3 | 1987-01-01 | |
| Cartonic | amrinone | Sanofi | amrinone | cGMP-inhibited 3',5'-cyclic phosphodiesterase A | 1984-01-01 | |
| Dobutamine Hydrochloride In Dextrose 5% In Plastic Container | Dobutamine Hydrochloride | Pfizer Inc. | Inotropic agent | Beta-receptors of the heart | 1978-01-01 | |
| Sodium Nitroprusside | NITROPRUSSIDE | Roche | Vasodilator | Atrial natriuretic peptide receptor 1 | 1974-01-01 | |
| Lasix | furosemide | Generic (originally Hoechst AG) | Loop Diuretic [EPC] | ATP-binding cassette sub-family G member 2, CDGSH iron-sulfur domain-containing protein 1, G-protein coupled receptor 35 | 1966-07-01 | |
| Torasemide | Torasemide | Medical University of Warsaw | Solute carrier family 12 member 1 | |||
| Frusemide | Frusemide | Melbourne Health | ATP-binding cassette sub-family G member 2, CDGSH iron-sulfur domain-containing protein 1, G-protein coupled receptor 35 | |||
| Dobutamin | Dobutamin | Competence Network for Congenital Heart Defects | Solute carrier family 22 member 1, Alpha-1D adrenergic receptor, Alpha-2B adrenergic receptor |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- Sanofi · 2 drugs in Decompensated cardiac failure
- · 2 drugs in Decompensated cardiac failure
- Generic (originally Hoechst AG) · 1 drug in Decompensated cardiac failure
- Medical University of Warsaw · 1 drug in Decompensated cardiac failure
- Melbourne Health · 1 drug in Decompensated cardiac failure
- Pfizer Inc. · 1 drug in Decompensated cardiac failure
- Roche · 1 drug in Decompensated cardiac failure
- Scios Llc · 1 drug in Decompensated cardiac failure
- Competence Network for Congenital Heart Defects · 1 drug in Decompensated cardiac failure
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Cite this brief
Drug Landscape (2026). Decompensated cardiac failure — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/decompensated-cardiac-failure. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing