Last reviewed · How we verify

Decompensated cardiac failure — Treatment Landscape & Competitive Intelligence

Decompensated cardiac failure (disease) competitive landscape: 9 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

9 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Decompensated cardiac failure, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Natrecor NESIRITIDE Scios Llc Natriuretic Peptide Atrial natriuretic peptide receptor 1 2001-01-01
Primacor MILRINONE Sanofi Phosphodiesterase 3 Inhibitor Phosphodiesterase 3 1987-01-01
Cartonic amrinone Sanofi amrinone cGMP-inhibited 3',5'-cyclic phosphodiesterase A 1984-01-01
Dobutamine Hydrochloride In Dextrose 5% In Plastic Container Dobutamine Hydrochloride Pfizer Inc. Inotropic agent Beta-receptors of the heart 1978-01-01
Sodium Nitroprusside NITROPRUSSIDE Roche Vasodilator Atrial natriuretic peptide receptor 1 1974-01-01
Lasix furosemide Generic (originally Hoechst AG) Loop Diuretic [EPC] ATP-binding cassette sub-family G member 2, CDGSH iron-sulfur domain-containing protein 1, G-protein coupled receptor 35 1966-07-01
Torasemide Torasemide Medical University of Warsaw Solute carrier family 12 member 1
Frusemide Frusemide Melbourne Health ATP-binding cassette sub-family G member 2, CDGSH iron-sulfur domain-containing protein 1, G-protein coupled receptor 35
Dobutamin Dobutamin Competence Network for Congenital Heart Defects Solute carrier family 22 member 1, Alpha-1D adrenergic receptor, Alpha-2B adrenergic receptor

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Sanofi · 2 drugs in Decompensated cardiac failure
  2. · 2 drugs in Decompensated cardiac failure
  3. Generic (originally Hoechst AG) · 1 drug in Decompensated cardiac failure
  4. Medical University of Warsaw · 1 drug in Decompensated cardiac failure
  5. Melbourne Health · 1 drug in Decompensated cardiac failure
  6. Pfizer Inc. · 1 drug in Decompensated cardiac failure
  7. Roche · 1 drug in Decompensated cardiac failure
  8. Scios Llc · 1 drug in Decompensated cardiac failure
  9. Competence Network for Congenital Heart Defects · 1 drug in Decompensated cardiac failure

Subscribe to ongoing alerts

Every new regulatory action, PDUFA date, or trial completion in Decompensated cardiac failure:

Cite this brief

Drug Landscape (2026). Decompensated cardiac failure — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/decompensated-cardiac-failure. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing