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Absence seizure — Treatment Landscape & Competitive Intelligence

Absence seizure (disease) competitive landscape: 10 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

10 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Absence seizure, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Depakene valproic acid Generic (originally Abbott/AbbVie) Anti-epileptic Agent [EPC] Alcohol dehydrogenase [NADP(+)], Histone deacetylase 1, Histone deacetylase 2 1978-02-28
Ativan lorazepam Generic (originally Wyeth/Pfizer) Benzodiazepine [EPC] GABA-A receptor alpha-1/beta-3/gamma-2, Fatty acid-binding protein, liver 1977-09-30
Klonopin clonazepam Generic (originally Roche) Benzodiazepine [EPC] GABA-A receptor alpha-1/beta-2/gamma-2, GABA-A receptor; anion channel, GABA-A receptor; anion channel 1975-06-04
Zarontin Ethosuximide Pfizer Succinimide Voltage-dependent T-type calcium channel subunit alpha-1G 1960-01-01
Celontin METHSUXIMIDE Pfizer Anti-epileptic Agent Voltage-gated T-type calcium channel 1957-01-01
Diamox ACETAZOLAMIDE Teva Carbonic Anhydrase Inhibitor [EPC] Carbonic anhydrase 1953-01-01
Klonopin Klonopin Par Pharmaceutical, Inc. GABA-A receptor alpha-1/beta-2/gamma-2, GABA-A receptor; anion channel, GABA-A receptor; anion channel
Epilim sodium valproate Sanofi Alcohol dehydrogenase [NADP(+)], Histone deacetylase 1, Histone deacetylase 2
Divalproex Divalproex University of Chicago Alcohol dehydrogenase [NADP(+)], Histone deacetylase 1, Histone deacetylase 2
mesuximide mesuximide Assistance Publique - Hôpitaux de Paris Voltage-gated T-type calcium channel

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Pfizer · 3 drugs in Absence seizure
  2. · 3 drugs in Absence seizure
  3. Generic (originally Abbott/AbbVie) · 1 drug in Absence seizure
  4. Generic (originally Roche) · 1 drug in Absence seizure
  5. Generic (originally Wyeth/Pfizer) · 1 drug in Absence seizure
  6. Par Pharmaceutical, Inc. · 1 drug in Absence seizure
  7. Sanofi · 1 drug in Absence seizure
  8. Teva · 1 drug in Absence seizure
  9. University of Chicago · 1 drug in Absence seizure
  10. Assistance Publique - Hôpitaux de Paris · 1 drug in Absence seizure

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Cite this brief

Drug Landscape (2026). Absence seizure — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/absence-seizure. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing