Who are Differin 0.3% Topical Gel's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Adapalene Gel, 0.1%, adapalene gel, 0.3%, Adapalene Lotion Vehicle, Adara 5% Cream US.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-06-10 · How we verify

Differin 0.3% Topical Gel — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Differin 0.3% Topical Gel (Differin 0.3% Topical Gel) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Retinoid (third-generation). Area: Dermatology.

phase 3 Retinoid (third-generation) Retinoic acid receptor gamma (RARγ) Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

Differin 0.3% Topical Gel (Differin 0.3% Topical Gel) — Aleor Dermaceuticals Limited. Adapalene is a third-generation retinoid that binds to retinoic acid receptors to normalize skin cell differentiation and reduce inflammation in acne.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Differin 0.3% Topical Gel TARGET	Differin 0.3% Topical Gel	Aleor Dermaceuticals Limited	phase 3	Retinoid (third-generation)	Retinoic acid receptor gamma (RARγ)
Adapalene Gel, 0.1%	Adapalene Gel, 0.1%	Galderma R&D	marketed	Retinoid (third-generation)	Retinoic acid receptors (RARα, RARβ, RARγ)
adapalene gel, 0.3%	adapalene gel, 0.3%	Galderma R&D	marketed	Retinoid (third-generation)	Retinoic acid receptors (RARγ, RARα, RARβ)
Adapalene Lotion Vehicle	Adapalene Lotion Vehicle	Galderma R&D	phase 3	Retinoid (third-generation)	Retinoic acid receptors (RARγ, RARα, RARβ)
Adara 5% Cream US	Adara 5% Cream US	Apotex Inc.	phase 3	Retinoid (third-generation)	Retinoic acid receptors (RARs)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Retinoid (third-generation) class)

Galderma R&D · 3 drugs in this class
Aleor Dermaceuticals Limited · 1 drug in this class
Apotex Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Differin 0.3% Topical Gel — Competitive Intelligence Brief. https://druglandscape.com/ci/differin-0-3-topical-gel. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing