Last reviewed · How we verify
Dexmedetomidine 0.5μg/kg — Competitive Intelligence Brief
marketed
Alpha-2 adrenergic receptor agonist
Alpha-2 adrenergic receptor
Anesthesia and Sedation
Small molecule
Live · refreshed every 30 min
Target snapshot
Dexmedetomidine 0.5μg/kg (Dexmedetomidine 0.5μg/kg) — Eye & ENT Hospital of Fudan University. Dexmedetomidine is a selective alpha-2 adrenergic receptor agonist that produces sedation, analgesia, and anxiolysis by activating presynaptic and postsynaptic alpha-2 receptors in the central nervous system.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Dexmedetomidine 0.5μg/kg TARGET | Dexmedetomidine 0.5μg/kg | Eye & ENT Hospital of Fudan University | marketed | Alpha-2 adrenergic receptor agonist | Alpha-2 adrenergic receptor | |
| Dexmedetomidine-Dexamethasone | Dexmedetomidine-Dexamethasone | University of Chile | marketed | Alpha-2 adrenergic agonist / Corticosteroid combination | Alpha-2 adrenergic receptor; Glucocorticoid receptor | |
| dexmedetomidine 0.25 µg/kg IV | dexmedetomidine 0.25 µg/kg IV | American University of Beirut Medical Center | marketed | Alpha-2 adrenergic receptor agonist | Alpha-2 adrenergic receptor | |
| clonidine (drug) intravenously | clonidine (drug) intravenously | Medical University of Vienna | marketed | Alpha-2 adrenergic agonist | Alpha-2 adrenergic receptor | |
| perineural dexmedetomidine | perineural dexmedetomidine | Guangzhou Women and Children's Medical Center | marketed | Alpha-2 adrenergic agonist | Alpha-2 adrenergic receptor | |
| Dexmedetomidine 0.75 microgram/kg | Dexmedetomidine 0.75 microgram/kg | Sindh Institute of Urology and Transplantation | marketed | Alpha-2 adrenergic receptor agonist | Alpha-2 adrenergic receptor | |
| mometasone furoate + Oxymetazoline | mometasone furoate + Oxymetazoline | Guangzhou Women and Children's Medical Center | marketed | Intranasal corticosteroid + nasal decongestant combination | Glucocorticoid receptor (mometasone); alpha-2 adrenergic receptor (oxymetazoline) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Alpha-2 adrenergic receptor agonist class)
- Allergan · 3 drugs in this class
- Eye & ENT Hospital of Fudan University · 2 drugs in this class
- National Cancer Institute, Egypt · 2 drugs in this class
- The University of Hong Kong · 2 drugs in this class
- Sindh Institute of Urology and Transplantation · 2 drugs in this class
- Fayoum University Hospital · 1 drug in this class
- First Affiliated Hospital of Chongqing Medical University · 1 drug in this class
- Guangzhou General Hospital of Guangzhou Military Command · 1 drug in this class
- Icahn School of Medicine at Mount Sinai · 1 drug in this class
- KAT General Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Dexmedetomidine 0.5μg/kg — Competitive Intelligence Brief. https://druglandscape.com/ci/dexmedetomidine-0-5-g-kg. Accessed 2026-05-17.
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