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Dexmedetomidine 0.5μg/kg — Competitive Intelligence Brief

Dexmedetomidine 0.5μg/kg (Dexmedetomidine 0.5μg/kg) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Alpha-2 adrenergic receptor agonist. Area: Anesthesia and Sedation.

marketed Alpha-2 adrenergic receptor agonist Alpha-2 adrenergic receptor Anesthesia and Sedation Small molecule Live · refreshed every 30 min

Target snapshot

Dexmedetomidine 0.5μg/kg (Dexmedetomidine 0.5μg/kg) — Eye & ENT Hospital of Fudan University. Dexmedetomidine is a selective alpha-2 adrenergic receptor agonist that produces sedation, analgesia, and anxiolysis by activating presynaptic and postsynaptic alpha-2 receptors in the central nervous system.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Dexmedetomidine 0.5μg/kg TARGET Dexmedetomidine 0.5μg/kg Eye & ENT Hospital of Fudan University marketed Alpha-2 adrenergic receptor agonist Alpha-2 adrenergic receptor
Dexmedetomidine-Dexamethasone Dexmedetomidine-Dexamethasone University of Chile marketed Alpha-2 adrenergic agonist / Corticosteroid combination Alpha-2 adrenergic receptor; Glucocorticoid receptor
dexmedetomidine 0.25 µg/kg IV dexmedetomidine 0.25 µg/kg IV American University of Beirut Medical Center marketed Alpha-2 adrenergic receptor agonist Alpha-2 adrenergic receptor
clonidine (drug) intravenously clonidine (drug) intravenously Medical University of Vienna marketed Alpha-2 adrenergic agonist Alpha-2 adrenergic receptor
perineural dexmedetomidine perineural dexmedetomidine Guangzhou Women and Children's Medical Center marketed Alpha-2 adrenergic agonist Alpha-2 adrenergic receptor
Dexmedetomidine 0.75 microgram/kg Dexmedetomidine 0.75 microgram/kg Sindh Institute of Urology and Transplantation marketed Alpha-2 adrenergic receptor agonist Alpha-2 adrenergic receptor
mometasone furoate + Oxymetazoline mometasone furoate + Oxymetazoline Guangzhou Women and Children's Medical Center marketed Intranasal corticosteroid + nasal decongestant combination Glucocorticoid receptor (mometasone); alpha-2 adrenergic receptor (oxymetazoline)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Alpha-2 adrenergic receptor agonist class)

  1. Allergan · 3 drugs in this class
  2. Eye & ENT Hospital of Fudan University · 2 drugs in this class
  3. National Cancer Institute, Egypt · 2 drugs in this class
  4. The University of Hong Kong · 2 drugs in this class
  5. Sindh Institute of Urology and Transplantation · 2 drugs in this class
  6. Fayoum University Hospital · 1 drug in this class
  7. First Affiliated Hospital of Chongqing Medical University · 1 drug in this class
  8. Guangzhou General Hospital of Guangzhou Military Command · 1 drug in this class
  9. Icahn School of Medicine at Mount Sinai · 1 drug in this class
  10. KAT General Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Dexmedetomidine 0.5μg/kg — Competitive Intelligence Brief. https://druglandscape.com/ci/dexmedetomidine-0-5-g-kg. Accessed 2026-05-17.

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