Who are Degarelix (LHRH antagonist)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Lupron, Micronor, cetrorelix (cetrotide), Dual Trigger, Leuprolide (GnRH agonists), Ultra-Long GnRH Agonists + Letrozole.

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Last reviewed 2026-05-16 · How we verify

Degarelix (LHRH antagonist) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Degarelix (LHRH antagonist) (Degarelix (LHRH antagonist)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: GnRH antagonist. Area: Oncology.

marketed GnRH antagonist GnRH receptor Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Degarelix (LHRH antagonist) (Degarelix (LHRH antagonist)) — Rabin Medical Center. Degarelix is a gonadotropin-releasing hormone (GnRH) antagonist that rapidly suppresses luteinizing hormone and follicle-stimulating hormone, leading to testosterone suppression.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Degarelix (LHRH antagonist) TARGET	Degarelix (LHRH antagonist)	Rabin Medical Center	marketed	GnRH antagonist	GnRH receptor
Lupron	leuprorelin	Accord Healthcare S.L.U.	marketed	Gonadotropin Releasing Hormone Receptor Agonist	GnRH receptors	1985-01-01
Micronor	norethisterone	Johnson & Johnson	marketed	Progestin	GnRH receptors	1962-01-01
cetrorelix (cetrotide)	cetrorelix (cetrotide)	Eugonia	marketed	GnRH antagonist	GnRH receptor
Dual Trigger	Dual Trigger	Weill Medical College of Cornell University	marketed	Reproductive hormone protocol	GnRH receptor and LH receptor
Leuprolide (GnRH agonists)	Leuprolide (GnRH agonists)	University of Pisa	marketed	GnRH agonist	GnRH receptor (GNRHR)
Ultra-Long GnRH Agonists + Letrozole	Ultra-Long GnRH Agonists + Letrozole	University of Palermo	marketed	GnRH agonist + aromatase inhibitor combination	GnRH receptor; aromatase (CYP19A1)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2028-03-22 — Lupron · 9617303 · US
2031-02-05 — Lupron · 8921326 · US

Sponsor landscape (GnRH antagonist class)

Jiangsu HengRui Medicine Co., Ltd. · 2 drugs in this class
Instituto Valenciano de Infertilidad, IVI VALENCIA · 2 drugs in this class
AEterna Zentaris · 2 drugs in this class
El Shatby University Hospital for Obstetrics and Gynecology · 1 drug in this class
Eugonia · 1 drug in this class
Instituto de Investigacion Sanitaria La Fe · 1 drug in this class
Merck KGaA, Darmstadt, Germany · 1 drug in this class
Rabin Medical Center · 1 drug in this class
Sumitomo Pharma Switzerland GmbH · 1 drug in this class
University of Edinburgh · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Degarelix (LHRH antagonist) — Competitive Intelligence Brief. https://druglandscape.com/ci/degarelix-lhrh-antagonist. Accessed 2026-05-16.

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