Definity infusion — Competitive Intelligence Brief

Definity infusion (Definity infusion) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Ultrasound contrast agent. Area: Cardiology / Diagnostic Imaging.

marketed Ultrasound contrast agent Cardiology / Diagnostic Imaging Small molecule

Target snapshot

Definity infusion (Definity infusion) — Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University. Definity is an ultrasound contrast agent composed of perflutren-filled microbubbles that enhance echocardiographic imaging by increasing ultrasound backscatter from the left ventricular cavity.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Definity infusion TARGET	Definity infusion	Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University	marketed	Ultrasound contrast agent
Optison echocardiography contrast agent	Optison echocardiography contrast agent	University of Utah	marketed	Ultrasound contrast agent
Contrast-Enhanced Ultrasound using Lumason	Contrast-Enhanced Ultrasound using Lumason	Children's Hospital of Philadelphia	marketed	Ultrasound contrast agent
Perflutren lipid	Perflutren lipid	UNC Lineberger Comprehensive Cancer Center	marketed	Ultrasound contrast agent
Sonovue and Sonazoid	Sonovue and Sonazoid	Second Affiliated Hospital, School of Medicine, Zhejiang University	phase 3	Ultrasound contrast agent
SonoVue-enhanced ultrasound	SonoVue-enhanced ultrasound	Bracco Diagnostics, Inc	phase 3	Ultrasound contrast agent
SonoVue®	SonoVue®	GE Healthcare	phase 3	Ultrasound contrast agent

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Ultrasound contrast agent class)

1. Second Affiliated Hospital, School of Medicine, Zhejiang University · 2 drugs in this class
2. Bracco Diagnostics, Inc · 1 drug in this class
3. Centre Hospitalier Régional Metz-Thionville · 1 drug in this class
4. Children's Hospital of Philadelphia · 1 drug in this class
5. GE Healthcare · 1 drug in this class
6. Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University · 1 drug in this class
7. Sunnybrook Health Sciences Centre · 1 drug in this class
8. UNC Lineberger Comprehensive Cancer Center · 1 drug in this class
9. University of Utah · 1 drug in this class
10. Acusphere · 1 drug in this class