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SonoVue-enhanced ultrasound
SonoVue-enhanced ultrasound is a Ultrasound contrast agent Small molecule drug developed by Bracco Diagnostics, Inc. It is currently in Phase 3 development for Enhancement of ultrasound imaging for detection and characterization of focal lesions in liver, breast, and other organs, Assessment of myocardial perfusion and left ventricular opacification in echocardiography. Also known as: sulfur hexafluoride microbubbles.
SonoVue is a microbubble contrast agent that enhances ultrasound imaging by reflecting ultrasound waves, improving visualization of blood flow and tissue perfusion.
SonoVue is a microbubble contrast agent that enhances ultrasound imaging by reflecting ultrasound waves, improving visualization of blood flow and tissue perfusion. Used for Enhancement of ultrasound imaging for detection and characterization of focal lesions in liver, breast, and other organs, Assessment of myocardial perfusion and left ventricular opacification in echocardiography.
At a glance
| Generic name | SonoVue-enhanced ultrasound |
|---|---|
| Also known as | sulfur hexafluoride microbubbles |
| Sponsor | Bracco Diagnostics, Inc |
| Drug class | Ultrasound contrast agent |
| Modality | Small molecule |
| Therapeutic area | Diagnostic Imaging |
| Phase | Phase 3 |
Mechanism of action
SonoVue consists of sulfur hexafluoride microbubbles stabilized by a phospholipid shell. When injected intravenously, these microbubbles circulate through the vasculature and strongly reflect ultrasound waves, creating enhanced contrast in ultrasound images. This allows clinicians to better visualize perfusion patterns, detect lesions, and assess tissue viability in real-time.
Approved indications
- Enhancement of ultrasound imaging for detection and characterization of focal lesions in liver, breast, and other organs
- Assessment of myocardial perfusion and left ventricular opacification in echocardiography
Common side effects
- Headache
- Flushing
- Chest discomfort
- Nausea
- Hypersensitivity reactions
Key clinical trials
- Sonoporation and Tumor Microenvironment Response in Colorectal Liver Metastases (NA)
- CEUS Evaluation of Hydrocephalus in Neonates and Infants (PHASE2)
- PlaCEUS: Feasibility Study of Contrast-enhanced Ultrasound to Visualize Maternal Uterine Spiral Arteries Postpartum. (NA)
- Contrast Enhanced Ultrasound to Evaluate Response to Chemoembolization in Patients With Liver Tumors (PHASE2)
- Contrast-Enhanced Ultrasound Imaging for Diagnosing Recurrent Renal Cell Carcinoma (RCC) Post Ablation (PHASE2)
- Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses (PHASE1)
- Liver Cirrhosis Complicated by Clinically Significant Portal Hypertension (NA)
- Neonatal Brain Ultrasound With CEUS and Elastography (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- SonoVue-enhanced ultrasound CI brief — competitive landscape report
- SonoVue-enhanced ultrasound updates RSS · CI watch RSS
- Bracco Diagnostics, Inc portfolio CI
Frequently asked questions about SonoVue-enhanced ultrasound
What is SonoVue-enhanced ultrasound?
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Related
- Drug class: All Ultrasound contrast agent drugs
- Manufacturer: Bracco Diagnostics, Inc — full pipeline
- Therapeutic area: All drugs in Diagnostic Imaging
- Indication: Drugs for Enhancement of ultrasound imaging for detection and characterization of focal lesions in liver, breast, and other organs
- Indication: Drugs for Assessment of myocardial perfusion and left ventricular opacification in echocardiography
- Also known as: sulfur hexafluoride microbubbles
- Compare: SonoVue-enhanced ultrasound vs similar drugs
- Pricing: SonoVue-enhanced ultrasound cost, discount & access