Who are Decitabine in combination with R-CHOP's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Decitabine plus HAAG regimen, Decitabine combined with HAAG Regimen.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Decitabine in combination with R-CHOP — Competitive Intelligence Brief

Decitabine in combination with R-CHOP (Decitabine in combination with R-CHOP) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Hypomethylating agent combined with chemotherapy regimen. Area: Oncology.

phase 3 Hypomethylating agent combined with chemotherapy regimen DNA methyltransferase (decitabine component); CD20, topoisomerase II, microtubule dynamics (R-CHOP components) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Decitabine in combination with R-CHOP (Decitabine in combination with R-CHOP) — Second Affiliated Hospital of Nanchang University. Decitabine inhibits DNA methyltransferase to reactivate silenced tumor suppressor genes, while R-CHOP chemotherapy directly kills lymphoma cells through multiple mechanisms.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Decitabine in combination with R-CHOP TARGET	Decitabine in combination with R-CHOP	Second Affiliated Hospital of Nanchang University	phase 3	Hypomethylating agent combined with chemotherapy regimen	DNA methyltransferase (decitabine component); CD20, topoisomerase II, microtubule dynamics (R-CHOP components)
Decitabine plus HAAG regimen	Decitabine plus HAAG regimen	The First Affiliated Hospital of Soochow University	phase 3	Hypomethylating agent combined with chemotherapy regimen	DNA methyltransferase (DNMT)
Decitabine combined with HAAG Regimen	Decitabine combined with HAAG Regimen	The First Affiliated Hospital of Soochow University	phase 3	Hypomethylating agent combined with chemotherapy regimen	DNA methyltransferase (DNMT); also targets topoisomerase II and DNA synthesis

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Hypomethylating agent combined with chemotherapy regimen class)

The First Affiliated Hospital of Soochow University · 2 drugs in this class
Second Affiliated Hospital of Nanchang University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Decitabine in combination with R-CHOP — Competitive Intelligence Brief. https://druglandscape.com/ci/decitabine-in-combination-with-r-chop. Accessed 2026-05-16.

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