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Decitabine combined with HAAG Regimen — Competitive Intelligence Brief
Target snapshot
Decitabine combined with HAAG Regimen (Decitabine combined with HAAG Regimen) — The First Affiliated Hospital of Soochow University. Decitabine inhibits DNA methyltransferase to reactivate silenced tumor suppressor genes, combined with HAAG chemotherapy (cytarabine, aclarubicin, amsacrine, granulocyte colony-stimulating factor) to enhance cytotoxic effects in hematologic malignancies.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Decitabine combined with HAAG Regimen TARGET | Decitabine combined with HAAG Regimen | The First Affiliated Hospital of Soochow University | phase 3 | Hypomethylating agent combined with chemotherapy regimen | DNA methyltransferase (DNMT); also targets topoisomerase II and DNA synthesis | |
| Decitabine plus HAAG regimen | Decitabine plus HAAG regimen | The First Affiliated Hospital of Soochow University | phase 3 | Hypomethylating agent combined with chemotherapy regimen | DNA methyltransferase (DNMT) | |
| Decitabine in combination with R-CHOP | Decitabine in combination with R-CHOP | Second Affiliated Hospital of Nanchang University | phase 3 | Hypomethylating agent combined with chemotherapy regimen | DNA methyltransferase (decitabine component); CD20, topoisomerase II, microtubule dynamics (R-CHOP components) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Hypomethylating agent combined with chemotherapy regimen class)
- The First Affiliated Hospital of Soochow University · 2 drugs in this class
- Second Affiliated Hospital of Nanchang University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Decitabine combined with HAAG Regimen — Competitive Intelligence Brief. https://druglandscape.com/ci/decitabine-combined-with-haag-regimen. Accessed 2026-05-18.
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