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DA5221-B2 — Competitive Intelligence Brief

DA5221-B2 (DA5221-B2) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: GLP-1/GIP receptor agonist. Area: Endocrinology.

phase 3 GLP-1/GIP receptor agonist GLP-1R, GIPR Endocrinology Small molecule Live · refreshed every 30 min

Target snapshot

DA5221-B2 (DA5221-B2) — Dong-A ST Co., Ltd.. DA5221-B2 is a dual GLP-1/GIP receptor agonist that activates both glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors to improve glycemic control and promote weight loss.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
DA5221-B2 TARGET DA5221-B2 Dong-A ST Co., Ltd. phase 3 GLP-1/GIP receptor agonist GLP-1R, GIPR
Continue GLP/GIP Continue GLP/GIP The Cleveland Clinic marketed GLP-1/GIP receptor agonist GLP-1R, GIPR
Treatment with tirzapatide Treatment with tirzapatide University Medical Centre Ljubljana marketed GLP-1/GIP receptor agonist GLP-1R, GIPR
AC2993 AC2993 AstraZeneca phase 3 Dual GLP-1/GIP receptor agonist GLP-1R, GIPR
DA5221-T2 DA5221-T2 Dong-A ST Co., Ltd. phase 3 GLP-1/GIP receptor agonist GLP-1R, GIPR
DWJ211 DWJ211 Daewoong Pharmaceutical Co. LTD. phase 3 Dual GLP-1/GIP receptor agonist GLP-1R, GIPR
IcoSema IcoSema Novo Nordisk A/S phase 3 GLP-1/GIP receptor agonist GLP-1R, GIPR

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (GLP-1/GIP receptor agonist class)

  1. Dong-A ST Co., Ltd. · 2 drugs in this class
  2. Hanmi Pharmaceutical Company Limited · 1 drug in this class
  3. Novo Nordisk A/S · 1 drug in this class
  4. The Cleveland Clinic · 1 drug in this class
  5. University Medical Centre Ljubljana · 1 drug in this class

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Cite this brief

Drug Landscape (2026). DA5221-B2 — Competitive Intelligence Brief. https://druglandscape.com/ci/da5221-b2. Accessed 2026-05-13.

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