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CsA+MMF+CS — Competitive Intelligence Brief
marketed
Immunosuppressive combination therapy
Calcineurin (CsA); IMPDH type II (MMF); glucocorticoid receptor (CS)
Immunology / Transplantation
Small molecule
Live · refreshed every 30 min
Target snapshot
CsA+MMF+CS (CsA+MMF+CS) — Pfizer. This combination suppresses the immune system through multiple pathways: cyclosporine inhibits T-cell activation, mycophenolate mofetil blocks lymphocyte proliferation, and corticosteroids broadly dampen inflammatory responses.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CsA+MMF+CS TARGET | CsA+MMF+CS | Pfizer | marketed | Immunosuppressive combination therapy | Calcineurin (CsA); IMPDH type II (MMF); glucocorticoid receptor (CS) | |
| Kidney transplant maintenance immunosuppression | Kidney transplant maintenance immunosuppression | Imperial College Healthcare NHS Trust | marketed | Immunosuppressive combination therapy | ||
| Dexamethasone Azathioprine Pulse therapy | Dexamethasone Azathioprine Pulse therapy | Jinnah Postgraduate Medical Centre | marketed | Immunosuppressive combination therapy | Glucocorticoid receptor (dexamethasone); inosine monophosphate dehydrogenase (azathioprine) | |
| Zenapax®, CellCept® and prednisolone | Zenapax®, CellCept® and prednisolone | University of Oslo School of Pharmacy | marketed | Immunosuppressive combination therapy | IL-2 receptor (daclizumab); inosine monophosphate dehydrogenase (mycophenolate mofetil); glucocorticoid receptor (prednisolone) | |
| ATG/PTCy | ATG/PTCy | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | marketed | Immunosuppressive combination therapy | ||
| ATG+mycophénolate mofétil+tacrolimus | ATG+mycophénolate mofétil+tacrolimus | University Hospital, Toulouse | marketed | Immunosuppressive combination therapy | T lymphocytes (ATG); IMPDH (mycophenolate mofetil); calcineurin (tacrolimus) | |
| Basiliximab, Tacrolimus, MMF | Basiliximab, Tacrolimus, MMF | University Hospital Freiburg | marketed | Immunosuppressive combination therapy | IL-2 receptor (basiliximab); calcineurin (tacrolimus); IMPDH (MMF) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Immunosuppressive combination therapy class)
- University Hospital, Brest · 2 drugs in this class
- Pfizer · 2 drugs in this class
- Fundação Pró Rim · 2 drugs in this class
- Haukeland University Hospital · 1 drug in this class
- Imperial College Healthcare NHS Trust · 1 drug in this class
- Jinnah Postgraduate Medical Centre · 1 drug in this class
- Novartis · 1 drug in this class
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · 1 drug in this class
- Swiss Cancer Institute · 1 drug in this class
- University Hospital Freiburg · 1 drug in this class
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Cite this brief
Drug Landscape (2026). CsA+MMF+CS — Competitive Intelligence Brief. https://druglandscape.com/ci/csa-mmf-cs. Accessed 2026-05-13.
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