Who are COX-2 inhibitor's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Cox2 inhibitor (Celecoxib), Parecoxib and remifentanil, Cox-2, parecoxib, valdecoxib, etoricoxib, MK0966; rofecoxib, Etoricoxib + Tizanidine fixed dose.

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Last reviewed 2026-06-10 · How we verify

COX-2 inhibitor — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

COX-2 inhibitor (COX-2 inhibitor) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: COX-2 selective inhibitor. Area: Rheumatology / Pain Management.

phase 3 COX-2 selective inhibitor COX-2 (Cyclooxygenase-2) Rheumatology / Pain Management Small molecule Live · refreshed every 30 min

Target snapshot

COX-2 inhibitor (COX-2 inhibitor) — Seoul National University Hospital. COX-2 inhibitors selectively block cyclooxygenase-2 enzyme to reduce prostaglandin production and inflammation without significantly affecting COX-1-mediated gastric protection.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
COX-2 inhibitor TARGET	COX-2 inhibitor	Seoul National University Hospital	phase 3	COX-2 selective inhibitor	COX-2 (Cyclooxygenase-2)
Cox2 inhibitor (Celecoxib)	Cox2 inhibitor (Celecoxib)	Seoul National University Hospital	marketed	COX-2 selective inhibitor (coxib)	COX-2 (Cyclooxygenase-2)
Parecoxib and remifentanil	Parecoxib and remifentanil	Ullevaal University Hospital	marketed	COX-2 selective inhibitor (parecoxib) and opioid agonist (remifentanil)	COX-2 (parecoxib); mu-opioid receptor (remifentanil)
Cox-2	Cox-2	First Affiliated Hospital Xi'an Jiaotong University	marketed	Cox-2 selective inhibitor (NSAID)	Cyclooxygenase-2 (Cox-2)
parecoxib, valdecoxib, etoricoxib	parecoxib, valdecoxib, etoricoxib	Asker & Baerum Hospital	marketed	COX-2 selective inhibitor (coxib)	COX-2 (cyclooxygenase-2)
MK0966; rofecoxib	MK0966; rofecoxib	Merck Sharp & Dohme LLC	marketed	COX-2 selective inhibitor (coxib)	COX-2 (cyclooxygenase-2)
Etoricoxib + Tizanidine fixed dose	Etoricoxib + Tizanidine fixed dose	Laboratorios Silanes S.A. de C.V.	phase 3	COX-2 selective inhibitor + centrally-acting muscle relaxant	COX-2 enzyme; alpha-2 adrenergic receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (COX-2 selective inhibitor class)

Seoul National University Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). COX-2 inhibitor — Competitive Intelligence Brief. https://druglandscape.com/ci/cox-2-inhibitor. Accessed 2026-06-10.

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