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Global Alliance for TB Drug Development — Portfolio Competitive Intelligence Brief

Global Alliance for TB Drug Development pipeline: 2 marketed, 0 filed, 3 Phase 3, 2 Phase 2. Recent regulatory actions, upcoming PDUFA, patent timeline, top competitor overlap.

2 marketed 0 filed 3 Phase 3 2 Phase 2 7 Phase 1 Live · 30-min refresh

Portfolio leaders (marketed + Phase 3 / filed)

DrugGenericPhaseClassTargetAreaFirst approval
HR HR marketed Anti-tuberculosis agent (fixed-dose combination) Mycobacterial cell wall (isoniazid) and bacterial RNA polymerase (rifampicin) Infectious Disease
Moxifloxacin (M) Moxifloxacin (M) marketed Fluoroquinolone antibiotic DNA gyrase; Topoisomerase IV Infectious Disease
HRZE HRZE phase 3 Fixed-dose combination antituberculous agent Multiple: KatG/InhA (isoniazid), bacterial RNA polymerase (rifampicin), PncA/RpoB (pyrazinamide), arabinosyl transferase (ethambutol) Infectious Disease
Pyrazinamide (Z) Pyrazinamide (Z) phase 3 Nicotinamide analog; antituberculous agent Pantothenate synthetase (PanC); pyrazinamidase activation Infectious Disease
Moxifloxacin, Ethambutol, Isoniazid, Pyrazinamide & Rifampicin Moxifloxacin, Ethambutol, Isoniazid, Pyrazinamide & Rifampicin phase 3 Anti-tuberculosis agent combination Multiple: DNA gyrase (moxifloxacin), RNA polymerase (rifampicin), mycolic acid synthesis (isoniazid, pyrazinamide), arabinosyl transferase (ethambutol) Infectious Disease

Therapeutic area mix

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this portfolio.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this portfolio.

Patent timeline (forward window)

No upcoming patent expiries for this portfolio.

Competitive overlap (companies sharing drug classes)

  1. Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections · 1 shared drug class
  2. Allergan · 1 shared drug class
  3. Bayer · 1 shared drug class
  4. Bayer AG · 1 shared drug class
  5. Carolina Eyecare Physicians, LLC · 1 shared drug class
  6. Connect Biopharma Australia Pty Ltd · 1 shared drug class
  7. Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) · 1 shared drug class
  8. ANRS, Emerging Infectious Diseases · 1 shared drug class

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Cite this brief

Drug Landscape (2026). Global Alliance for TB Drug Development — Portfolio Competitive Intelligence Brief. https://druglandscape.com/ci/company/global-alliance-for-tb-drug-development. Accessed 2026-05-16.

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