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Global Alliance for TB Drug Development — Portfolio Competitive Intelligence Brief
2 marketed
0 filed
3 Phase 3
2 Phase 2
7 Phase 1
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Portfolio leaders (marketed + Phase 3 / filed)
| Drug | Generic | Phase | Class | Target | Area | First approval |
|---|---|---|---|---|---|---|
| HR | HR | marketed | Anti-tuberculosis agent (fixed-dose combination) | Mycobacterial cell wall (isoniazid) and bacterial RNA polymerase (rifampicin) | Infectious Disease | |
| Moxifloxacin (M) | Moxifloxacin (M) | marketed | Fluoroquinolone antibiotic | DNA gyrase; Topoisomerase IV | Infectious Disease | |
| HRZE | HRZE | phase 3 | Fixed-dose combination antituberculous agent | Multiple: KatG/InhA (isoniazid), bacterial RNA polymerase (rifampicin), PncA/RpoB (pyrazinamide), arabinosyl transferase (ethambutol) | Infectious Disease | |
| Pyrazinamide (Z) | Pyrazinamide (Z) | phase 3 | Nicotinamide analog; antituberculous agent | Pantothenate synthetase (PanC); pyrazinamidase activation | Infectious Disease | |
| Moxifloxacin, Ethambutol, Isoniazid, Pyrazinamide & Rifampicin | Moxifloxacin, Ethambutol, Isoniazid, Pyrazinamide & Rifampicin | phase 3 | Anti-tuberculosis agent combination | Multiple: DNA gyrase (moxifloxacin), RNA polymerase (rifampicin), mycolic acid synthesis (isoniazid, pyrazinamide), arabinosyl transferase (ethambutol) | Infectious Disease |
Therapeutic area mix
- Infectious Disease · 5
- Other · 1
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Competitive overlap (companies sharing drug classes)
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections · 1 shared drug class
- Allergan · 1 shared drug class
- Bayer · 1 shared drug class
- Bayer AG · 1 shared drug class
- Carolina Eyecare Physicians, LLC · 1 shared drug class
- Connect Biopharma Australia Pty Ltd · 1 shared drug class
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) · 1 shared drug class
- ANRS, Emerging Infectious Diseases · 1 shared drug class
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Cite this brief
Drug Landscape (2026). Global Alliance for TB Drug Development — Portfolio Competitive Intelligence Brief. https://druglandscape.com/ci/company/global-alliance-for-tb-drug-development. Accessed 2026-05-16.