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CO-1.01 — Competitive Intelligence Brief
phase 2
PARP inhibitor
PARP (poly(ADP-ribose) polymerase)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
CO-1.01 (CO-1.01) — Clovis Oncology, Inc.. CO-1.01 is a poly(ADP-ribose) polymerase (PARP) inhibitor that blocks DNA repair mechanisms in cancer cells, leading to cell death.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CO-1.01 TARGET | CO-1.01 | Clovis Oncology, Inc. | phase 2 | PARP inhibitor | PARP (poly(ADP-ribose) polymerase) | |
| Talazoparib with enzalutamide | talazoparib-with-enzalutamide | Pfizer | marketed | PARP inhibitor and androgen receptor inhibitor | PARP enzymes and androgen receptor | Not yet launched |
| Talzenna | Talazoparib Tosylate | Pfizer Inc. | marketed | PARP inhibitor | PARP1 and PARP2 enzymes | |
| Pharmacokinetics, Dosage of Niraparib | Pharmacokinetics, Dosage of Niraparib | Hospices Civils de Lyon | marketed | PARP inhibitor | PARP1, PARP2 | |
| Olaparib Treatment D | Olaparib Treatment D | AstraZeneca | marketed | PARP inhibitor | PARP1, PARP2 | |
| Placebo matching Niraparib | Placebo matching Niraparib | Tesaro, Inc. | phase 3 | PARP inhibitor (reference: niraparib) | PARP1/PARP2 (reference target) | |
| Iniparib (SAR240550/BSI-201) | Iniparib (SAR240550/BSI-201) | Sanofi | phase 3 | PARP inhibitor | PARP (poly(ADP-ribose) polymerase) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (PARP inhibitor class)
- AstraZeneca · 5 drugs in this class
- BeiGene · 2 drugs in this class
- Clovis Oncology, Inc. · 1 drug in this class
- Fondazione Ricerca Traslazionale · 1 drug in this class
- GERCOR - Multidisciplinary Oncology Cooperative Group · 1 drug in this class
- Hospices Civils de Lyon · 1 drug in this class
- Pfizer Inc. · 1 drug in this class
- Sanofi · 1 drug in this class
- Tesaro, Inc. · 1 drug in this class
- The First Affiliated Hospital of Xiamen University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). CO-1.01 — Competitive Intelligence Brief. https://druglandscape.com/ci/co-1-01. Accessed 2026-05-13.
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