CNS 7056 — Competitive Intelligence Brief

CNS 7056 (CNS 7056) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Opioid receptor antagonist. Area: Pain.

phase 2 Opioid receptor antagonist Kappa opioid receptor Pain Small molecule

Target snapshot

CNS 7056 (CNS 7056) — Paion UK Ltd.. CNS 7056 is a kappa opioid receptor antagonist.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
CNS 7056 TARGET	CNS 7056	Paion UK Ltd.	phase 2	Opioid receptor antagonist	Kappa opioid receptor
BENZHYDROCODONE	BENZHYDROCODONE		marketed	Opioid analgesic combination; full mu-opioid agonist with non-opioid analgesic	Mu-opioid receptors (primary); delta and kappa opioid receptors (secondary); central nervous system pain pathways	2018-01-01
NALBUPHINE HYDROCHLORIDE	NALBUPHINE HYDROCHLORIDE		marketed		kappa opioid receptors, mu opioid receptors	1979-01-01
Opioid group	Opioid group	Beijing Friendship Hospital	marketed	Opioid agonist	Mu opioid receptor (primary), delta opioid receptor, kappa opioid receptor
Diluted Deodorized Tincture of Opium	Diluted Deodorized Tincture of Opium	Eastern Maine Medical Center	marketed	Opioid agonist	Mu opioid receptor (primary), delta opioid receptor, kappa opioid receptor
Naltrexone Tablet and Placebo Patch	Naltrexone Tablet and Placebo Patch	The Scripps Research Institute	marketed	Opioid receptor antagonist	Mu, delta, and kappa opioid receptors
opioid pain pills	opioid pain pills	Rush University Medical Center	marketed	Opioid analgesic	Mu opioid receptor (primary); delta and kappa opioid receptors (secondary)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Opioid receptor antagonist class)

1. Albert Einstein Healthcare Network · 1 drug in this class
2. Cephalon · 1 drug in this class
3. Leiden University Medical Center · 1 drug in this class
4. New York State Psychiatric Institute · 1 drug in this class
5. Paion UK Ltd. · 1 drug in this class
6. Pocket Naloxone Corp · 1 drug in this class
7. State University of New York - Upstate Medical University · 1 drug in this class
8. Texas Tech University · 1 drug in this class
9. The Scripps Research Institute · 1 drug in this class
10. University of North Carolina, Chapel Hill · 1 drug in this class