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Clopidogrel active metabolite — Competitive Intelligence Brief
marketed
P2Y12 receptor antagonist / Antiplatelet agent
P2Y12 receptor
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Clopidogrel active metabolite (Clopidogrel active metabolite) — University of Florida. Clopidogrel active metabolite irreversibly inhibits platelet P2Y12 adenosine diphosphate receptors, preventing platelet aggregation and thrombus formation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Clopidogrel active metabolite TARGET | Clopidogrel active metabolite | University of Florida | marketed | P2Y12 receptor antagonist / Antiplatelet agent | P2Y12 receptor | |
| Clopidogrel reloading | Clopidogrel reloading | University of Pecs | marketed | P2Y12 receptor antagonist / Thienopyridine antiplatelet agent | P2Y12 receptor | |
| OAC + clopicogrel | OAC + clopicogrel | St. Antonius Hospital | marketed | Anticoagulant + antiplatelet agent combination | Coagulation cascade (OAC) and P2Y12 receptor (clopidogrel) | |
| bivalirudin + clopidogrel + aspirin | bivalirudin + clopidogrel + aspirin | Centre Hospitalier de PAU | marketed | Anticoagulant + antiplatelet combination | Thrombin (Factor IIa), P2Y12 receptor, cyclooxygenase | |
| Clopidogrel, cilostazol | Clopidogrel, cilostazol | Kyunghee University Medical Center | marketed | Antiplatelet agent combination | P2Y12 receptor (clopidogrel); phosphodiesterase-3 (cilostazol) | |
| prasugrel/bivalirudin | prasugrel/bivalirudin | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | marketed | Antiplatelet agent + Direct thrombin inhibitor combination | P2Y12 receptor (prasugrel); Thrombin (bivalirudin) | |
| Crushed ticagrelor, morphine,metoclopramide | Crushed ticagrelor, morphine,metoclopramide | Collegium Medicum w Bydgoszczy | marketed | Antiplatelet agent + opioid analgesic + antiemetic (combination therapy) | P2Y12 receptor (ticagrelor); mu opioid receptors (morphine); dopamine D2 receptors (metoclopramide) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (P2Y12 receptor antagonist / Antiplatelet agent class)
- Centre hospitalier de l'Université de Montréal (CHUM) · 1 drug in this class
- Jeil Pharmaceutical Co., Ltd. · 1 drug in this class
- University of Florida · 1 drug in this class
- VA Office of Research and Development · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Clopidogrel active metabolite — Competitive Intelligence Brief. https://druglandscape.com/ci/clopidogrel-active-metabolite. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing