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Clopidogrel active metabolite — Competitive Intelligence Brief

Clopidogrel active metabolite (Clopidogrel active metabolite) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: P2Y12 receptor antagonist / Antiplatelet agent. Area: Cardiovascular.

marketed P2Y12 receptor antagonist / Antiplatelet agent P2Y12 receptor Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Clopidogrel active metabolite (Clopidogrel active metabolite) — University of Florida. Clopidogrel active metabolite irreversibly inhibits platelet P2Y12 adenosine diphosphate receptors, preventing platelet aggregation and thrombus formation.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Clopidogrel active metabolite TARGET Clopidogrel active metabolite University of Florida marketed P2Y12 receptor antagonist / Antiplatelet agent P2Y12 receptor
Clopidogrel reloading Clopidogrel reloading University of Pecs marketed P2Y12 receptor antagonist / Thienopyridine antiplatelet agent P2Y12 receptor
OAC + clopicogrel OAC + clopicogrel St. Antonius Hospital marketed Anticoagulant + antiplatelet agent combination Coagulation cascade (OAC) and P2Y12 receptor (clopidogrel)
bivalirudin + clopidogrel + aspirin bivalirudin + clopidogrel + aspirin Centre Hospitalier de PAU marketed Anticoagulant + antiplatelet combination Thrombin (Factor IIa), P2Y12 receptor, cyclooxygenase
Clopidogrel, cilostazol Clopidogrel, cilostazol Kyunghee University Medical Center marketed Antiplatelet agent combination P2Y12 receptor (clopidogrel); phosphodiesterase-3 (cilostazol)
prasugrel/bivalirudin prasugrel/bivalirudin I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio marketed Antiplatelet agent + Direct thrombin inhibitor combination P2Y12 receptor (prasugrel); Thrombin (bivalirudin)
Crushed ticagrelor, morphine,metoclopramide Crushed ticagrelor, morphine,metoclopramide Collegium Medicum w Bydgoszczy marketed Antiplatelet agent + opioid analgesic + antiemetic (combination therapy) P2Y12 receptor (ticagrelor); mu opioid receptors (morphine); dopamine D2 receptors (metoclopramide)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (P2Y12 receptor antagonist / Antiplatelet agent class)

  1. Centre hospitalier de l'Université de Montréal (CHUM) · 1 drug in this class
  2. Jeil Pharmaceutical Co., Ltd. · 1 drug in this class
  3. University of Florida · 1 drug in this class
  4. VA Office of Research and Development · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Clopidogrel active metabolite — Competitive Intelligence Brief. https://druglandscape.com/ci/clopidogrel-active-metabolite. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing