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cisplatin + capecitabine — Competitive Intelligence Brief

cisplatin + capecitabine (cisplatin + capecitabine) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Chemotherapy combination (platinum agent + antimetabolite). Area: Oncology.

phase 3 Chemotherapy combination (platinum agent + antimetabolite) DNA (cisplatin); thymidylate synthase (capecitabine) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

cisplatin + capecitabine (cisplatin + capecitabine) — AstraZeneca. Cisplatin crosslinks DNA to prevent replication while capecitabine is converted to fluorouracil to inhibit thymidylate synthase, together blocking cancer cell division and survival.

Comparator set (3 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
cisplatin + capecitabine TARGET cisplatin + capecitabine AstraZeneca phase 3 Chemotherapy combination (platinum agent + antimetabolite) DNA (cisplatin); thymidylate synthase (capecitabine)
Cisplatin,fluorouracil Cisplatin,fluorouracil Sun Yat-sen University phase 3 Chemotherapy combination (platinum agent + antimetabolite) DNA (direct cross-linking and antimetabolite incorporation)
Carboplatin, 5FU concomitant Carboplatin, 5FU concomitant Groupe Oncologie Radiotherapie Tete et Cou phase 3 Chemotherapy combination (platinum agent + antimetabolite) DNA (carboplatin); thymidylate synthase (5FU)
cisplatin and fluorouracil cisplatin and fluorouracil Sun Yat-sen University phase 3 Chemotherapy combination (platinum agent + antimetabolite) DNA (cisplatin); thymidylate synthase and nucleotide metabolism (fluorouracil)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Chemotherapy combination (platinum agent + antimetabolite) class)

  1. Sun Yat-sen University · 2 drugs in this class
  2. AstraZeneca · 1 drug in this class
  3. Groupe Oncologie Radiotherapie Tete et Cou · 1 drug in this class

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Cite this brief

Drug Landscape (2026). cisplatin + capecitabine — Competitive Intelligence Brief. https://druglandscape.com/ci/cisplatin-capecitabine. Accessed 2026-05-17.

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