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cisplatin + capecitabine — Competitive Intelligence Brief
phase 3
Chemotherapy combination (platinum agent + antimetabolite)
DNA (cisplatin); thymidylate synthase (capecitabine)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
cisplatin + capecitabine (cisplatin + capecitabine) — AstraZeneca. Cisplatin crosslinks DNA to prevent replication while capecitabine is converted to fluorouracil to inhibit thymidylate synthase, together blocking cancer cell division and survival.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| cisplatin + capecitabine TARGET | cisplatin + capecitabine | AstraZeneca | phase 3 | Chemotherapy combination (platinum agent + antimetabolite) | DNA (cisplatin); thymidylate synthase (capecitabine) | |
| Cisplatin,fluorouracil | Cisplatin,fluorouracil | Sun Yat-sen University | phase 3 | Chemotherapy combination (platinum agent + antimetabolite) | DNA (direct cross-linking and antimetabolite incorporation) | |
| Carboplatin, 5FU concomitant | Carboplatin, 5FU concomitant | Groupe Oncologie Radiotherapie Tete et Cou | phase 3 | Chemotherapy combination (platinum agent + antimetabolite) | DNA (carboplatin); thymidylate synthase (5FU) | |
| cisplatin and fluorouracil | cisplatin and fluorouracil | Sun Yat-sen University | phase 3 | Chemotherapy combination (platinum agent + antimetabolite) | DNA (cisplatin); thymidylate synthase and nucleotide metabolism (fluorouracil) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Chemotherapy combination (platinum agent + antimetabolite) class)
- Sun Yat-sen University · 2 drugs in this class
- AstraZeneca · 1 drug in this class
- Groupe Oncologie Radiotherapie Tete et Cou · 1 drug in this class
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Cite this brief
Drug Landscape (2026). cisplatin + capecitabine — Competitive Intelligence Brief. https://druglandscape.com/ci/cisplatin-capecitabine. Accessed 2026-05-17.
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