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cisplatin and fluorouracil — Competitive Intelligence Brief
phase 3
Chemotherapy combination (platinum agent + antimetabolite)
DNA (cisplatin); thymidylate synthase and nucleotide metabolism (fluorouracil)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
cisplatin and fluorouracil (cisplatin and fluorouracil) — Sun Yat-sen University. Cisplatin and fluorouracil work together as a chemotherapy combination to damage cancer cell DNA and inhibit nucleotide synthesis, preventing tumor growth and proliferation.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| cisplatin and fluorouracil TARGET | cisplatin and fluorouracil | Sun Yat-sen University | phase 3 | Chemotherapy combination (platinum agent + antimetabolite) | DNA (cisplatin); thymidylate synthase and nucleotide metabolism (fluorouracil) | |
| Cisplatin,fluorouracil | Cisplatin,fluorouracil | Sun Yat-sen University | phase 3 | Chemotherapy combination (platinum agent + antimetabolite) | DNA (direct cross-linking and antimetabolite incorporation) | |
| Carboplatin, 5FU concomitant | Carboplatin, 5FU concomitant | Groupe Oncologie Radiotherapie Tete et Cou | phase 3 | Chemotherapy combination (platinum agent + antimetabolite) | DNA (carboplatin); thymidylate synthase (5FU) | |
| cisplatin + capecitabine | cisplatin + capecitabine | AstraZeneca | phase 3 | Chemotherapy combination (platinum agent + antimetabolite) | DNA (cisplatin); thymidylate synthase (capecitabine) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Chemotherapy combination (platinum agent + antimetabolite) class)
- Sun Yat-sen University · 2 drugs in this class
- AstraZeneca · 1 drug in this class
- Groupe Oncologie Radiotherapie Tete et Cou · 1 drug in this class
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Cite this brief
Drug Landscape (2026). cisplatin and fluorouracil — Competitive Intelligence Brief. https://druglandscape.com/ci/cisplatin-and-fluorouracil. Accessed 2026-05-17.
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