Last reviewed · How we verify
CBT-001 single dose — Competitive Intelligence Brief
phase 2
CD47/SIRPα axis inhibitor
CD47
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
CBT-001 single dose (CBT-001 single dose) — Cloudbreak Therapeutics, LLC. CBT-001 is a small molecule that targets the CD47/SIRPα axis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CBT-001 single dose TARGET | CBT-001 single dose | Cloudbreak Therapeutics, LLC | phase 2 | CD47/SIRPα axis inhibitor | CD47 | |
| KI1106 4g, QD | KI1106 4g, QD | Kuhnil Pharmaceutical Co., Ltd. | phase 3 | CD47/SIRPα inhibitor | CD47/SIRPα axis | |
| Treatment Choice (TC) | Treatment Choice (TC) | Astex Pharmaceuticals, Inc. | phase 3 | SIRPα inhibitor | CD47 | |
| HP-802-247 | HP-802-247 | Healthpoint | phase 3 | CD47 antibody | CD47 | |
| MB-102 OMID | MB-102 OMID | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | phase 3 | CD47 inhibitor | CD47 | |
| Open single period A140 | Open single period A140 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | phase 3 | CD47 inhibitor | CD47 | |
| CHS-1420 | CHS-1420 | Coherus Oncology, Inc. | phase 3 | Bispecific antibody | CD47 and CD40 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (CD47/SIRPα axis inhibitor class)
- Akeso · 1 drug in this class
- AltruBio Inc. · 1 drug in this class
- Bristol-Myers Squibb · 1 drug in this class
- City of Hope Medical Center · 1 drug in this class
- Cloudbreak Therapeutics, LLC · 1 drug in this class
- Sinocelltech Ltd. · 1 drug in this class
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- CBT-001 single dose CI watch — RSS
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- CBT-001 single dose CI watch — JSON
- CBT-001 single dose alone — RSS
- Whole CD47/SIRPα axis inhibitor class — RSS
Cite this brief
Drug Landscape (2026). CBT-001 single dose — Competitive Intelligence Brief. https://druglandscape.com/ci/cbt-001-single-dose. Accessed 2026-05-14.
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