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KI1106 4g, QD
KI1106 is a small molecule targeting the CD47/SIRPα axis.
KI1106 is a small molecule targeting the CD47/SIRPα axis. Used for Relapsed or refractory multiple myeloma.
At a glance
| Generic name | KI1106 4g, QD |
|---|---|
| Sponsor | Kuhnil Pharmaceutical Co., Ltd. |
| Drug class | CD47/SIRPα inhibitor |
| Target | CD47/SIRPα axis |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 3 |
Mechanism of action
KI1106 works by blocking the interaction between CD47 and SIRPα, which is involved in immune evasion by cancer cells. This blockade leads to the activation of macrophages and enhanced anti-tumor immune responses.
Approved indications
- Relapsed or refractory multiple myeloma
Common side effects
- Fatigue
- Nausea
- Diarrhea
- Vomiting
- Anemia
- Thrombocytopenia
- Neutropenia
- Leukopenia
- Anorexia
- Weight loss
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- KI1106 4g, QD CI brief — competitive landscape report
- KI1106 4g, QD updates RSS · CI watch RSS
- Kuhnil Pharmaceutical Co., Ltd. portfolio CI