Last reviewed · How we verify

KI1106 4g, QD

Kuhnil Pharmaceutical Co., Ltd. · Phase 3 active Small molecule

KI1106 is a small molecule targeting the CD47/SIRPα axis.

KI1106 is a small molecule targeting the CD47/SIRPα axis. Used for Relapsed or refractory multiple myeloma.

At a glance

Generic nameKI1106 4g, QD
SponsorKuhnil Pharmaceutical Co., Ltd.
Drug classCD47/SIRPα inhibitor
TargetCD47/SIRPα axis
ModalitySmall molecule
Therapeutic areaOncology
PhasePhase 3

Mechanism of action

KI1106 works by blocking the interaction between CD47 and SIRPα, which is involved in immune evasion by cancer cells. This blockade leads to the activation of macrophages and enhanced anti-tumor immune responses.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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