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MB-102 OMID

Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. · Phase 3 active Small molecule Under review

MB-102 OMID is a CD47 inhibitor Small molecule drug developed by Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.. It is currently in Phase 3 development for Relapsed or refractory multiple myeloma. Also known as: Relmapirazin.

MB-102 OMID is a monoclonal antibody targeting CD47.

MB-102 OMID is a small molecule used in the treatment of kidney diseases, including kidney injury and kidney failure. It is being studied in a clinical trial (NCT05943977) to evaluate its efficacy and bioequivalence in Chinese participants.

Likelihood of approval
61.3% vs 58.3% industry baseline
If approved by FDA: likely 2028–2030
Steps remaining: NDA/BLA submission
Confidence: High
Why this estimate
  • Baseline phase 3 → approval rate +58.3pp
    Industry-wide phase 3 drugs reach approval ~58.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
  • Oncology Phase 3 boost +3.0pp
    Oncology Phase 3 trials have higher approval rates (~61%) than the cross-industry average due to clearer endpoints and FDA oncology pathway.
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2028–2030
EMA EU 2029–2031 +0.7 yr
MHRA GB 2029–2031 +0.7 yr
Health Canada CA 2029–2032 +0.9 yr
TGA AU 2029–2032 +1.2 yr
PMDA JP 2029–2032 +1.5 yr
NMPA CN 2030–2033 +2.3 yr
MFDS KR 2029–2032 +1.4 yr
CDSCO IN 2029–2033 +1.8 yr
ANVISA BR 2030–2033 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameMB-102 OMID
Also known asRelmapirazin
SponsorHangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Drug classCD47 inhibitor
TargetCD47
ModalitySmall molecule
Therapeutic areaOncology
PhasePhase 3

Mechanism of action

CD47 is a protein that inhibits phagocytosis, and by targeting it, MB-102 OMID aims to stimulate the immune system to attack cancer cells.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about MB-102 OMID

What is MB-102 OMID?

MB-102 OMID is a CD47 inhibitor drug developed by Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd., indicated for Relapsed or refractory multiple myeloma.

How does MB-102 OMID work?

MB-102 OMID is a monoclonal antibody targeting CD47.

What is MB-102 OMID used for?

MB-102 OMID is indicated for Relapsed or refractory multiple myeloma.

Who makes MB-102 OMID?

MB-102 OMID is developed by Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. (see full Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. pipeline at /company/hangzhou-zhongmei-huadong-pharmaceutical-co-ltd).

Is MB-102 OMID also known as anything else?

MB-102 OMID is also known as Relmapirazin.

What drug class is MB-102 OMID in?

MB-102 OMID belongs to the CD47 inhibitor class. See all CD47 inhibitor drugs at /class/cd47-inhibitor.

What development phase is MB-102 OMID in?

MB-102 OMID is in Phase 3.

What are the side effects of MB-102 OMID?

Common side effects of MB-102 OMID include Fatigue, Nausea, Diarrhea.

What does MB-102 OMID target?

MB-102 OMID targets CD47 and is a CD47 inhibitor.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing