Bupivacain/levobupivacaine — Competitive Intelligence Brief

Bupivacain/levobupivacaine (Bupivacain/levobupivacaine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Anesthesia.

marketed Local anesthetic Voltage-gated sodium channels Anesthesia Small molecule

Target snapshot

Bupivacain/levobupivacaine (Bupivacain/levobupivacaine) — University Hospital, Basel, Switzerland. Bupivacaine and levobupivacaine are local anesthetics that block sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacain/levobupivacaine TARGET	Bupivacain/levobupivacaine	University Hospital, Basel, Switzerland	marketed	Local anesthetic	Voltage-gated sodium channels
Phrenic nerve block with Ropivacaine	Phrenic nerve block with Ropivacaine	Odense University Hospital	marketed	Local anesthetic	Voltage-gated sodium channels
Orotracheal Lidocaine Oral Spray application	Orotracheal Lidocaine Oral Spray application	Abant Izzet Baysal University	marketed	Local anesthetic	Voltage-gated sodium channels
Nebulized lidocaine and dexmedetomidine	Nebulized lidocaine and dexmedetomidine	Ain Shams University	marketed	Local anesthetic and sedative-analgesic combination	Voltage-gated sodium channels (lidocaine); alpha-2 adrenergic receptors (dexmedetomidine)
Trigger point injection with bupivacaine	Trigger point injection with bupivacaine	George Washington University	marketed	Local anesthetic	Voltage-gated sodium channels
TAC alternate gel	TAC alternate gel	The University of Texas Health Science Center, Houston	marketed	Topical local anesthetic	Voltage-gated sodium channels
Lidocaine Hydrochloride Preservative Free	Lidocaine Hydrochloride	Pfizer Inc.	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels (Nav)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class