Who are Bovine thrombin's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Thrombin JMI, RiaSTAP, Tisseel Fibrin Sealant, Fibrin Sealant (Artiss), Fibrinogen Concentrate Human, EVARREST™.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Bovine thrombin — Competitive Intelligence Brief

Bovine thrombin (Bovine thrombin) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Coagulation factor / Hemostatic agent. Area: Hematology / Hemostasis.

marketed Coagulation factor / Hemostatic agent Fibrinogen Hematology / Hemostasis Biologic Live · refreshed every 30 min

Target snapshot

Bovine thrombin (Bovine thrombin) — Instituto Grifols, S.A.. Bovine thrombin is a serine protease that directly converts fibrinogen to fibrin, promoting blood clotting and hemostasis.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Bovine thrombin TARGET	Bovine thrombin	Instituto Grifols, S.A.	marketed	Coagulation factor / Hemostatic agent	Fibrinogen
Thrombin JMI	Thrombin JMI	University of Kansas Medical Center	marketed	Topical hemostatic agent	Fibrinogen
RiaSTAP	RiaSTAP	Weill Medical College of Cornell University	marketed	Fibrinogen concentrate	Fibrinogen (Factor I)
Tisseel Fibrin Sealant	Tisseel Fibrin Sealant	Massachusetts General Hospital	marketed	Fibrin sealant	Fibrinogen (substrate for thrombin-catalyzed polymerization)
Fibrin Sealant (Artiss)	Fibrin Sealant (Artiss)	Nguyen, Davis B., M.D.	marketed	Fibrin sealant	Fibrinogen; thrombin substrate
Fibrinogen Concentrate Human	Fibrinogen Concentrate Human	IRCCS Policlinico S. Donato	marketed	Coagulation factor concentrate	Fibrinogen (Factor I)
EVARREST™	EVARREST™	Ethicon, Inc.	marketed	Topical hemostatic agent	Fibrinogen (Factor I) and thrombin (Factor IIa)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Coagulation factor / Hemostatic agent class)

Instituto Grifols, S.A. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Bovine thrombin — Competitive Intelligence Brief. https://druglandscape.com/ci/bovine-thrombin. Accessed 2026-05-14.

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