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Botulinum Toxin A (Botox ) — Competitive Intelligence Brief
marketed
Neurotoxin; acetylcholine release inhibitor
SNARE proteins (specifically SNAP-25); acetylcholine release machinery
Neurology; Dermatology; Aesthetics
Small molecule
Live · refreshed every 30 min
Target snapshot
Botulinum Toxin A (Botox ) (Botulinum Toxin A (Botox )) — Assistance Publique - Hôpitaux de Paris. Botulinum toxin A blocks the release of acetylcholine at the neuromuscular junction by cleaving SNARE proteins, causing temporary muscle paralysis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Botulinum Toxin A (Botox ) TARGET | Botulinum Toxin A (Botox ) | Assistance Publique - Hôpitaux de Paris | marketed | Neurotoxin; acetylcholine release inhibitor | SNARE proteins (specifically SNAP-25); acetylcholine release machinery | |
| Nuceiva | BOTULINUM TOXIN TYPE A | GlaxoSmithKline K.K. | marketed | Acetylcholine Release Inhibitor [EPC] | Synaptosomal-associated protein 25 | 2019-01-01 |
| Xeomin | INCOBOTULINUMTOXINA | Merz Pharms | marketed | Acetylcholine Release Inhibitor [EPC] | 2015-01-01 | |
| Botox | ONABOTULINUMTOXINA | Allergan | marketed | Acetylcholine Release Inhibitor [EPC] | SNAP-25 | 2010-01-01 |
| Myobloc | RIMABOTULINUMTOXINB | Elan Pharm | marketed | Acetylcholine Release Inhibitor [EPC] | 2009-01-01 | |
| Botulinum toxin A | Botulinum toxin A | University of Calgary | marketed | Neurotoxin; Acetylcholine release inhibitor | SNAP-25 (synaptosome-associated protein of 25 kDa) | |
| Placebo / Botulinum Toxin A | Placebo / Botulinum Toxin A | Walter Reed Army Medical Center | marketed | Neurotoxin / Acetylcholine release inhibitor | SNAP-25 (synaptosome-associated protein of 25 kDa) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Neurotoxin; acetylcholine release inhibitor class)
- Allergan · 2 drugs in this class
- Assistance Publique - Hôpitaux de Paris · 1 drug in this class
- Croma-Pharma GmbH · 1 drug in this class
- NYU Langone Health · 1 drug in this class
- The University of Texas Health Science Center, Houston · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Botulinum Toxin A (Botox ) — Competitive Intelligence Brief. https://druglandscape.com/ci/botulinum-toxin-a-botox. Accessed 2026-05-17.
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