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Bifonazole spray once daily — Competitive Intelligence Brief
phase 2
azole antifungal
lanosterol 14α-demethylase
Infectious Diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
Bifonazole spray once daily (Bifonazole spray once daily) — Bayer. Bifonazole is an antifungal agent that works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Bifonazole spray once daily TARGET | Bifonazole spray once daily | Bayer | phase 2 | azole antifungal | lanosterol 14α-demethylase | |
| Topical Clotrimazole cream | Topical Clotrimazole cream | Hayat Abad Medical Complex, Peshawar | marketed | Imidazole antifungal | Fungal lanosterol 14α-demethylase (CYP51) | |
| Canesten® | Canesten® | Ache Laboratorios Farmaceuticos S.A. | marketed | Imidazole antifungal | Lanosterol 14α-demethylase (CYP51) | |
| Ketoconazole 2% | Ketoconazole 2% | University of California, Davis | marketed | Imidazole antifungal | Fungal cytochrome P450 (CYP51 / lanosterol 14α-demethylase) | |
| Terconazole Vaginal Suppository | Terconazole Vaginal Suppository | Hatem AbuHashim | marketed | Azole antifungal | Lanosterol 14α-demethylase (CYP51) | |
| Voriconazole clinical practice | Voriconazole clinical practice | Instituto de Investigación Hospital Universitario La Paz | marketed | Triazole antifungal | Fungal cytochrome P450 lanosterol 14α-demethylase (CYP51) | |
| fast itraconazole tablet | fast itraconazole tablet | University of Maryland, Baltimore | marketed | Triazole antifungal | Fungal cytochrome P450 lanosterol 14α-demethylase (CYP51) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (azole antifungal class)
- Bayer · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Bifonazole spray once daily — Competitive Intelligence Brief. https://druglandscape.com/ci/bifonazole-spray-once-daily. Accessed 2026-05-16.
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