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AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP — Competitive Intelligence Brief
phase 3
Antiretroviral combination therapy (NRTI + NNRTI or NRTI + NNRTI)
HIV reverse transcriptase, HIV integrase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP (AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP) — SEARCH Research Foundation. These are combination antiretroviral regimens that inhibit HIV reverse transcriptase and protease to suppress viral replication.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP TARGET | AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP | SEARCH Research Foundation | phase 3 | Antiretroviral combination therapy (NRTI + NNRTI or NRTI + NNRTI) | HIV reverse transcriptase, HIV integrase | |
| Atripla or Stribild | Atripla or Stribild | Fred Hutchinson Cancer Center | marketed | Antiretroviral combination therapy (NRTI/NNRTI or INSTI-based) | HIV reverse transcriptase, HIV integrase | |
| TDF/3TC/EFV or DTG or NVP | TDF/3TC/EFV or DTG or NVP | MU-JHU CARE | marketed | Antiretroviral combination therapy (NRTI + NNRTI or INSTI) | HIV reverse transcriptase, HIV integrase | |
| efavirenz + emtricitabina + tenofovir | efavirenz + emtricitabina + tenofovir | Hospital Universitari Vall d'Hebron Research Institute | marketed | Antiretroviral combination therapy (NNRTI + NRTI + NtRTI) | HIV reverse transcriptase, HIV integrase | |
| Atripla (r) | Atripla (r) | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Antiretroviral combination (NNRTI + NRTI + NtRTI) | HIV reverse transcriptase, HIV integrase | |
| Multiple Product PrEP Program | Multiple Product PrEP Program | University of Alabama at Birmingham | marketed | Antiretroviral combination therapy (nucleoside/nucleotide reverse transcriptase inhibitors) | HIV reverse transcriptase, HIV integrase | |
| Switch to Triumeq | Switch to Triumeq | McGill University Health Centre/Research Institute of the McGill University Health Centre | marketed | Antiretroviral combination therapy (NRTI + INSTI) | HIV reverse transcriptase, HIV integrase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination therapy (NRTI + NNRTI or NRTI + NNRTI) class)
- SEARCH Research Foundation · 1 drug in this class
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Cite this brief
Drug Landscape (2026). AZT/3TC/NVP, AZT/D4T/NVP, Truvada/NVP — Competitive Intelligence Brief. https://druglandscape.com/ci/azt-3tc-nvp-azt-d4t-nvp-truvada-nvp. Accessed 2026-05-18.
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