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ATB-346 low dose — Competitive Intelligence Brief
phase 2
NSAID
COX-2
Pain
Small molecule
Live · refreshed every 30 min
Target snapshot
ATB-346 low dose (ATB-346 low dose) — Antibe Therapeutics Inc.. ATB-346 low dose is a nonsteroidal anti-inflammatory drug (NSAID) that selectively targets COX-2 to reduce gastrointestinal toxicity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ATB-346 low dose TARGET | ATB-346 low dose | Antibe Therapeutics Inc. | phase 2 | NSAID | COX-2 | |
| Celebrex | celecoxib | Pfizer Inc. (originally Searle/Pharmacia) | marketed | Nonsteroidal Anti-inflammatory Drug [EPC] | COX-2 | 1998-12-31 |
| Cytotec | Misoprostol | Pfizer | marketed | NSAID combined with prostaglandin analog | Cyclooxygenase (COX-1 and COX-2); Prostaglandin receptors | 1988-01-01 |
| Codeine + Diclofenac | Codeine + Diclofenac | University of Sao Paulo | marketed | Opioid + NSAID combination analgesic | Mu opioid receptor (codeine); COX-1 and COX-2 (diclofenac) | |
| Diclofenac oral + Placebo Oral | Diclofenac oral + Placebo Oral | Hospital de Clinicas de Porto Alegre | marketed | Nonsteroidal anti-inflammatory drug (NSAID) | COX-1 and COX-2 | |
| Diclofenac sodium gel 3% | Diclofenac sodium gel 3% | LEO Pharma | marketed | NSAID (nonsteroidal anti-inflammatory drug) | COX-1 and COX-2 (cyclooxygenase enzymes) | |
| Escitalopram + Celecoxib | Escitalopram + Celecoxib | University of Pennsylvania | marketed | SSRI + selective COX-2 inhibitor combination | Serotonin transporter (SERT) and cyclooxygenase-2 (COX-2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Celebrex · 10722456 · Formulation · US
- — Celebrex · 10799517 · Formulation · US
- — Celebrex · 9949990 · Formulation · US
- — Celebrex · 9795620 · Formulation · US
- — Celebrex · 9572819 · Formulation · US
- — Celebrex · 10376527 · Formulation · US
Sponsor landscape (NSAID class)
- Antibe Therapeutics Inc. · 3 drugs in this class
- Iroko Pharmaceuticals, LLC · 3 drugs in this class
- Organon and Co · 2 drugs in this class
- Apsen Farmaceutica S.A. · 2 drugs in this class
- Amneal Pharmaceuticals, LLC · 2 drugs in this class
- Behar, Caren, M.D. · 2 drugs in this class
- IDEA AG · 2 drugs in this class
- Noven Pharmaceuticals, Inc. · 2 drugs in this class
- HALEON · 2 drugs in this class
- Pfizer · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). ATB-346 low dose — Competitive Intelligence Brief. https://druglandscape.com/ci/atb-346-low-dose. Accessed 2026-06-10.
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