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Aspirin loading dose — Competitive Intelligence Brief
marketed
Antiplatelet agent; nonsteroidal anti-inflammatory drug (NSAID)
Cyclooxygenase-1 (COX-1); Cyclooxygenase-2 (COX-2)
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Aspirin loading dose (Aspirin loading dose) — Icahn School of Medicine at Mount Sinai. Aspirin irreversibly inhibits cyclooxygenase (COX) enzymes to reduce thromboxane A2 production and platelet aggregation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Aspirin loading dose TARGET | Aspirin loading dose | Icahn School of Medicine at Mount Sinai | marketed | Antiplatelet agent; nonsteroidal anti-inflammatory drug (NSAID) | Cyclooxygenase-1 (COX-1); Cyclooxygenase-2 (COX-2) | |
| Plavix | clopidogrel | Generic (originally Sanofi/BMS) | marketed | Thienopyridine antiplatelet agent | Cytochrome P450 2B6, P2Y purinoceptor 12, Sodium-dependent serotonin transporter | 1997-11-17 |
| Aspirin | acetylsalicylic acid | Bayer AG | marketed | NSAID, Antiplatelet agent | Gamma-glutamyltranspeptidase 1, Nicotinate phosphoribosyltransferase, Acid-sensing ion channel 3 | 1899-03-06 |
| ASA | ASA | Biogen | marketed | Nonsteroidal anti-inflammatory drug (NSAID); antiplatelet agent | Cyclooxygenase-1 (COX-1); Cyclooxygenase-2 (COX-2) | |
| Dabigatran + clopidogrel | Dabigatran + clopidogrel | Zuyderland Medisch Centrum | marketed | Anticoagulant + antiplatelet agent combination | Thrombin (Factor IIa) and P2Y12 receptor | |
| Clopidogrel reloading | Clopidogrel reloading | University of Pecs | marketed | P2Y12 receptor antagonist / Thienopyridine antiplatelet agent | P2Y12 receptor | |
| Clopidogrel active metabolite | Clopidogrel active metabolite | University of Florida | marketed | P2Y12 receptor antagonist / Antiplatelet agent | P2Y12 receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiplatelet agent; nonsteroidal anti-inflammatory drug (NSAID) class)
- Icahn School of Medicine at Mount Sinai · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Aspirin loading dose — Competitive Intelligence Brief. https://druglandscape.com/ci/aspirin-loading-dose. Accessed 2026-05-13.
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