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Arsenic Trioxide Injectable Solution — Competitive Intelligence Brief

Arsenic Trioxide Injectable Solution (Arsenic Trioxide Injectable Solution) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Arsenic compound; differentiation agent and apoptosis inducer. Area: Oncology.

phase 2 Arsenic compound; differentiation agent and apoptosis inducer PML-RARA fusion protein; mitochondrial apoptotic pathway Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Arsenic Trioxide Injectable Solution (Arsenic Trioxide Injectable Solution) — Medsenic. Arsenic trioxide induces differentiation and apoptosis in leukemic cells, particularly in acute promyelocytic leukemia (APL), through multiple pathways including PML-RARA protein degradation and reactive oxygen species generation.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Arsenic Trioxide Injectable Solution TARGET Arsenic Trioxide Injectable Solution Medsenic phase 2 Arsenic compound; differentiation agent and apoptosis inducer PML-RARA fusion protein; mitochondrial apoptotic pathway
ATO ATO South China Children's Leukemia Group marketed Arsenic compound; differentiation agent PML-RARA fusion protein; mitochondrial apoptotic pathways
IV Arsenic Trioxide IV Arsenic Trioxide SDK Therapeutics, Inc. phase 3 Arsenic compound; differentiation agent and apoptosis inducer PML-RARA fusion protein; mitochondrial apoptotic pathway
Ibrutinib combined with As2O3 Ibrutinib combined with As2O3 Peking University People's Hospital phase 3 BTK inhibitor combined with arsenic compound BTK (Bruton's tyrosine kinase); As2O3 has multiple targets including PML-RARA fusion protein and mitochondrial pathways

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Arsenic compound; differentiation agent and apoptosis inducer class)

  1. Medsenic · 1 drug in this class
  2. SDK Therapeutics, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Arsenic Trioxide Injectable Solution — Competitive Intelligence Brief. https://druglandscape.com/ci/arsenic-trioxide-injectable-solution. Accessed 2026-05-15.

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