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Analogous GnRH antagonist — Competitive Intelligence Brief
phase 2
GnRH antagonist
GnRH receptor (GnRHR)
Oncology; Reproductive/Endocrinology
Small molecule
Live · refreshed every 30 min
Target snapshot
Analogous GnRH antagonist (Analogous GnRH antagonist) — Merck KGaA, Darmstadt, Germany. This GnRH antagonist blocks gonadotropin-releasing hormone receptors to suppress luteinizing hormone and follicle-stimulating hormone, reducing sex hormone production.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Analogous GnRH antagonist TARGET | Analogous GnRH antagonist | Merck KGaA, Darmstadt, Germany | phase 2 | GnRH antagonist | GnRH receptor (GnRHR) | |
| Cetrorelix and Leuprolide | Cetrorelix and Leuprolide | Instituto Valenciano de Infertilidad, IVI VALENCIA | marketed | GnRH antagonist and GnRH agonist combination | GnRH receptor | |
| Long acting FSH and GnRH antagonist | Long acting FSH and GnRH antagonist | Bioroma | marketed | GnRH antagonist / FSH receptor agonist combination | GnRH receptor, FSH receptor | |
| Antagon ™ | Antagon ™ | EMD Serono | marketed | GnRH antagonist | GnRH receptor | |
| Antagonist GnRH Cetrotide | Antagonist GnRH Cetrotide | Instituto Valenciano de Infertilidad, IVI VALENCIA | marketed | GnRH antagonist | GnRH receptor | |
| Degarelix (LHRH antagonist) | Degarelix (LHRH antagonist) | Rabin Medical Center | marketed | GnRH antagonist | GnRH receptor | |
| cetrorelix (cetrotide) | cetrorelix (cetrotide) | Eugonia | marketed | GnRH antagonist | GnRH receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (GnRH antagonist class)
- Jiangsu HengRui Medicine Co., Ltd. · 2 drugs in this class
- Instituto Valenciano de Infertilidad, IVI VALENCIA · 2 drugs in this class
- AEterna Zentaris · 2 drugs in this class
- El Shatby University Hospital for Obstetrics and Gynecology · 1 drug in this class
- Eugonia · 1 drug in this class
- Instituto de Investigacion Sanitaria La Fe · 1 drug in this class
- Merck KGaA, Darmstadt, Germany · 1 drug in this class
- Rabin Medical Center · 1 drug in this class
- Sumitomo Pharma Switzerland GmbH · 1 drug in this class
- University of Edinburgh · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Analogous GnRH antagonist — Competitive Intelligence Brief. https://druglandscape.com/ci/analogous-gnrh-antagonist. Accessed 2026-05-16.
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