Last reviewed · How we verify
Adapalene Lotion Vehicle — Competitive Intelligence Brief
phase 3
Retinoid (third-generation)
Retinoic acid receptors (RARγ, RARα, RARβ)
Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Adapalene Lotion Vehicle (Adapalene Lotion Vehicle) — Galderma R&D. Adapalene is a third-generation retinoid that binds to retinoic acid receptors to normalize skin cell differentiation and reduce inflammation in acne.
Comparator set (4 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Adapalene Lotion Vehicle TARGET | Adapalene Lotion Vehicle | Galderma R&D | phase 3 | Retinoid (third-generation) | Retinoic acid receptors (RARγ, RARα, RARβ) | |
| Adapalene Gel, 0.1% | Adapalene Gel, 0.1% | Galderma R&D | marketed | Retinoid (third-generation) | Retinoic acid receptors (RARα, RARβ, RARγ) | |
| adapalene gel, 0.3% | adapalene gel, 0.3% | Galderma R&D | marketed | Retinoid (third-generation) | Retinoic acid receptors (RARγ, RARα, RARβ) | |
| Adara 5% Cream US | Adara 5% Cream US | Apotex Inc. | phase 3 | Retinoid (third-generation) | Retinoic acid receptors (RARs) | |
| Differin 0.3% Topical Gel | Differin 0.3% Topical Gel | Aleor Dermaceuticals Limited | phase 3 | Retinoid (third-generation) | Retinoic acid receptor gamma (RARγ) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Retinoid (third-generation) class)
- Galderma R&D · 3 drugs in this class
- Aleor Dermaceuticals Limited · 1 drug in this class
- Apotex Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Adapalene Lotion Vehicle — Competitive Intelligence Brief. https://druglandscape.com/ci/adapalene-lotion-vehicle. Accessed 2026-05-16.
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