Who are adapalene lotion 0.1%'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Sohonos, Panretin, Targretin, Differin, Tegison, Accutane.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

adapalene lotion 0.1% — Competitive Intelligence Brief

adapalene lotion 0.1% (adapalene lotion 0.1%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Retinoid. Area: Dermatology.

phase 3 Retinoid Retinoic acid receptor Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

adapalene lotion 0.1% (adapalene lotion 0.1%) — Galderma R&D. Adapalene is a topical retinoid that works by binding to retinoic acid receptors, modulating gene expression and promoting cell turnover.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
adapalene lotion 0.1% TARGET	adapalene lotion 0.1%	Galderma R&D	phase 3	Retinoid	Retinoic acid receptor
Sohonos	PALOVAROTENE	Ipsen	marketed	Retinoid [EPC]	Retinoic acid receptor gamma	2023-01-01
Panretin	ALITRETINOIN	Advanz	marketed	Retinoid [EPC]	Retinoic acid receptor beta	1999-01-01
Targretin	BEXAROTENE	Bausch Health	marketed	Retinoid [EPC]	Retinoic acid receptor RXR-beta	1999-01-01
Differin	ADAPALENE	Galderma Labs Lp	marketed	Retinoid [EPC]	Retinoic acid receptor beta	1996-01-01
Tegison	ETRETINATE		marketed	Retinoid	Retinoic acid receptor RXR-gamma	1986-01-01
Accutane	ISOTRETINOIN		marketed	Retinoid [EPC]	Retinoic acid receptor alpha	1982-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-09-15 — Differin · 8435502 · Formulation · US
2026-09-15 — Differin · 8709392 · Formulation · US
2028-05-31 — Differin · 7998467 · Formulation · US
2035-05-29 — Accutane · 9750711 · Formulation · US
2035-08-04 — Accutane · 9700535 · Formulation · US

Sponsor landscape (Retinoid class)

Galderma R&D · 8 drugs in this class
Bausch Health Americas, Inc. · 4 drugs in this class
Stiefel, a GSK Company · 2 drugs in this class
Army Medical University, China · 1 drug in this class
Centro Dermatológico Dr. Ladislao de la Pascua · 1 drug in this class
Cipher Pharmaceuticals Inc. · 1 drug in this class
Center for Sight Las Vegas · 1 drug in this class
Dr. Reddy's Laboratories Limited · 1 drug in this class
Dr.dr.Irma Bernadette, SpKK (K) · 1 drug in this class
Dr. Emmy Graber · 1 drug in this class

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Cite this brief

Drug Landscape (2026). adapalene lotion 0.1% — Competitive Intelligence Brief. https://druglandscape.com/ci/adapalene-lotion-0-1. Accessed 2026-05-16.

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