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Active Comparator: Olaparib tablets — Competitive Intelligence Brief
phase 3
PARP inhibitor
PARP1, PARP2
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Active Comparator: Olaparib tablets (Active Comparator: Olaparib tablets) — AstraZeneca. Olaparib inhibits poly(ADP-ribose) polymerase (PARP) enzymes, preventing DNA repair in cancer cells and causing cell death, particularly in BRCA-mutant tumors.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Active Comparator: Olaparib tablets TARGET | Active Comparator: Olaparib tablets | AstraZeneca | phase 3 | PARP inhibitor | PARP1, PARP2 | |
| Talzenna | talazoparib-tosylate | Pfizer | marketed | Poly(ADP-Ribose) Polymerase Inhibitor | PARP1, PARP2 | 2018-01-01 |
| Olaparib Treatment D | Olaparib Treatment D | AstraZeneca | marketed | PARP inhibitor | PARP1, PARP2 | |
| Pharmacokinetics, Dosage of Niraparib | Pharmacokinetics, Dosage of Niraparib | Hospices Civils de Lyon | marketed | PARP inhibitor | PARP1, PARP2 | |
| Active comparator: Niraparib | Active comparator: Niraparib | Tesaro, Inc. | phase 3 | PARP inhibitor | PARP1, PARP2 | |
| Olaparib tablet | Olaparib tablet | Fondazione Ricerca Traslazionale | phase 3 | PARP inhibitor | PARP1, PARP2 | |
| Saruparib (AZD5305) | Saruparib (AZD5305) | AstraZeneca | phase 3 | PARP inhibitor | PARP1, PARP2 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Talzenna · 8420650 · US
- — Talzenna · 9820985 · US
- — Talzenna · 10780088 · US
- — Talzenna · 8012976 · US
- — Talzenna · 8735392 · US
- — Talzenna · 10189837 · US
Sponsor landscape (PARP inhibitor class)
- AstraZeneca · 5 drugs in this class
- BeiGene · 2 drugs in this class
- Clovis Oncology, Inc. · 1 drug in this class
- Fondazione Ricerca Traslazionale · 1 drug in this class
- GERCOR - Multidisciplinary Oncology Cooperative Group · 1 drug in this class
- Hospices Civils de Lyon · 1 drug in this class
- Pfizer Inc. · 1 drug in this class
- Sanofi · 1 drug in this class
- Tesaro, Inc. · 1 drug in this class
- The First Affiliated Hospital of Xiamen University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Active Comparator: Olaparib tablets — Competitive Intelligence Brief. https://druglandscape.com/ci/active-comparator-olaparib-tablets. Accessed 2026-05-14.
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