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ABX464 Repeated dose — Competitive Intelligence Brief
phase 1
Small molecule
RARγ
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
ABX464 Repeated dose (ABX464 Repeated dose) — Abivax S.A.. ABX464 is a small molecule antagonist of RARγ
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ABX464 Repeated dose TARGET | ABX464 Repeated dose | Abivax S.A. | phase 1 | Small molecule | RARγ | |
| adapalene gel, 0.3% | adapalene gel, 0.3% | Galderma R&D | marketed | Retinoid (third-generation) | Retinoic acid receptors (RARγ, RARα, RARβ) | |
| Topical Adapalene Gel 0.1% | Topical Adapalene Gel 0.1% | University of Louisville | marketed | Retinoid | Retinoic acid receptor gamma (RARγ) | |
| Adapalene Gel, 0.1% | Adapalene Gel, 0.1% | Galderma R&D | marketed | Retinoid (third-generation) | Retinoic acid receptors (RARα, RARβ, RARγ) | |
| Adapalene Lotion Vehicle | Adapalene Lotion Vehicle | Galderma R&D | phase 3 | Retinoid (third-generation) | Retinoic acid receptors (RARγ, RARα, RARβ) | |
| Adapalene 0,1% cream | Adapalene 0,1% cream | Dr.dr.Irma Bernadette, SpKK (K) | phase 3 | Retinoid | Retinoic acid receptor gamma (RARγ) | |
| Differin 0.3% Topical Gel | Differin 0.3% Topical Gel | Aleor Dermaceuticals Limited | phase 3 | Retinoid (third-generation) | Retinoic acid receptor gamma (RARγ) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Small molecule class)
- Pfizer · 3 drugs in this class
- Akorn, Inc. · 1 drug in this class
- Guangdong Hengrui Pharmaceutical Co., Ltd · 1 drug in this class
- Health Research, Inc. · 1 drug in this class
- Imperial College London · 1 drug in this class
- Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
- Nanjing Sanhome Pharmaceutical, Co., Ltd. · 1 drug in this class
- Second Affiliated Hospital of Wenzhou Medical University · 1 drug in this class
- UroGen Pharma Ltd. · 1 drug in this class
- Abivax S.A. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). ABX464 Repeated dose — Competitive Intelligence Brief. https://druglandscape.com/ci/abx464-repeated-dose. Accessed 2026-06-10.
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