Who are ABT-888's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Talazoparib with enzalutamide, Talzenna, NIRAPARIB, Rubraca, Pharmacokinetics, Dosage of Niraparib, Lynparza.

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Last reviewed 2026-05-13 · How we verify

ABT-888 — Competitive Intelligence Brief

ABT-888 (ABT-888) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: PARP inhibitor. Area: Oncology.

phase 2 PARP inhibitor PARP Oncology Small molecule Live · refreshed every 30 min

Target snapshot

ABT-888 (ABT-888) — AbbVie (prior sponsor, Abbott). ABT-888 is a PARP inhibitor that works by blocking the action of poly (ADP-ribose) polymerase (PARP) enzymes.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
ABT-888 TARGET	ABT-888	AbbVie (prior sponsor, Abbott)	phase 2	PARP inhibitor	PARP
Talazoparib with enzalutamide	talazoparib-with-enzalutamide	Pfizer	marketed	PARP inhibitor and androgen receptor inhibitor	PARP enzymes and androgen receptor	Not yet launched
Talzenna	talazoparib-tosylate	Pfizer	marketed	Poly(ADP-Ribose) Polymerase Inhibitor	PARP1, PARP2	2018-01-01
NIRAPARIB	NIRAPARIB		marketed		PARP-1, PARP-2, CYP17	2017-01-01
Rubraca	RUCAPARIB	Pfizer	marketed		PARP-1, PARP-2, PARP-3	2016-01-01
Pharmacokinetics, Dosage of Niraparib	Pharmacokinetics, Dosage of Niraparib	Hospices Civils de Lyon	marketed	PARP inhibitor	PARP1, PARP2
Lynparza	Lynparza	University of Texas Southwestern Medical Center	marketed		Mono [ADP-ribose] polymerase PARP16, Tankyrase-1, Tankyrase-2

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2029-07-27 — Talzenna · 8420650 · US
2029-07-27 — Talzenna · 9820985 · US
2029-07-27 — Talzenna · 10780088 · US
2029-10-19 — Talzenna · 8012976 · US
2031-10-20 — Talzenna · 8735392 · US
2031-10-20 — Talzenna · 10189837 · US

Sponsor landscape (PARP inhibitor class)

AstraZeneca · 5 drugs in this class
BeiGene · 2 drugs in this class
Clovis Oncology, Inc. · 1 drug in this class
Fondazione Ricerca Traslazionale · 1 drug in this class
GERCOR - Multidisciplinary Oncology Cooperative Group · 1 drug in this class
Hospices Civils de Lyon · 1 drug in this class
Pfizer Inc. · 1 drug in this class
Sanofi · 1 drug in this class
Tesaro, Inc. · 1 drug in this class
The First Affiliated Hospital of Xiamen University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ABT-888 — Competitive Intelligence Brief. https://druglandscape.com/ci/abt-888. Accessed 2026-05-13.

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