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NCT07523360
A Digital Cognitive Intervention for Intrusive Memories After Trauma
NA trial testing Pre-selected Trauma-related Cue Images with Eye Movement in Post-Traumatic Stress Disorder (PTSD) in 123 participants. Not yet recruiting.
10 February 2028
Quick facts
| Lead sponsor | Zhu Zijian |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 123 |
| Start date | 10 April 2026 |
| Primary completion | 10 February 2028 |
| Estimated completion | 10 May 2028 |
Drugs / interventions tested
- Pre-selected Trauma-related Cue Images with Eye Movement
- Patient-provided Trauma-related Cue Images with Eye Movement
- Neutral Images with Eye Movement
Conditions studied
- Post-Traumatic Stress Disorder (PTSD) — all drugs for Post-Traumatic Stress Disorder (PTSD) →
- Intrusive Memories of Traumatic Event(s) — all drugs for Intrusive Memories of Traumatic Event(s) →
Sponsor
Zhu Zijian
Who can join
Adults 18 to 50, any sex, with Post-Traumatic Stress Disorder (PTSD) or Intrusive Memories of Traumatic Event(s). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Intrusive traumatic memories frequently trigger severe distress and psychological disorders like PTSD. Traditional therapies require explicit trauma recall, which often causes severe patient distress and leads to treatment avoidance. To address this, our study introduces a novel, less aversive intervention combining unconscious visual processing with bilateral eye movement to mitigate these intrusive memories. Utilizing a randomized, three-arm design (comparing standardized trauma-related images, patient-provided images, and neutral images, all paired with bilateral eye movements), we plan to recruit participants who have experienced severe trauma and report ≥ 5 intrusive memories weekly, targeting a final sample of 40 patients per arm. The primary outcome is the frequency of intrusive memories. Secondary and additional outcomes include PTSD severity (CAPS-5, PCL-5, IES), depression, anxiety, borderline symptoms, functional improvements, subjective intervention distress, and dropout rates.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07523360
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Post-Traumatic Stress Disorder (PTSD)
Currently open trials in the same condition.
- NCT06194851 — Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07523360 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zhu Zijian
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07523360.
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