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NCT07507227: PI-FSNB
Perfusion Index for Assessing Femoral and Sciatic Nerve Block Success in Lower Extremity Surgery
NA trial testing Combined Femoral and Sciatic Nerve Block in Peripheral Nerve Block in 80 participants. Completed in 31 January 2019.
1 September 2018
Quick facts
| Lead sponsor | University of Gaziantep |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 80 |
| Start date | 1 June 2018 |
| Primary completion | 1 September 2018 |
| Estimated completion | 31 January 2019 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Combined Femoral and Sciatic Nerve Block
Conditions studied
- Peripheral Nerve Block — all drugs for Peripheral Nerve Block →
Sponsor
University of Gaziantep
Who can join
Adults 18 to 65, any sex, with Peripheral Nerve Block. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Peripheral nerve blocks are increasingly used in lower extremity surgery as an alternative to general anesthesia. However, traditional methods used to assess block success, such as sensory and motor testing, are subjective, time-consuming, and dependent on patient cooperation. The perfusion index (PI), measured non-invasively using pulse oximetry, reflects peripheral perfusion changes associated with sympathetic blockade and may serve as an early indicator of block effectiveness. This study aims to evaluate whether PI can be used as an early and reliable marker for assessing the success of combined femoral and sciatic nerve block in patients undergoing elective lower extremity surgery. A total of 80 patients aged 18-65 years with ASA physical status I-III will receive ultrasound- and nerve stimulator-guided combined femoral and sciatic nerve block. Hemodynamic parameters and perfusion-related variables, including PI, capillary refill time, and skin temperature, will be recorded at baseline and at 5, 10, 20, and 30 minutes after block administration. The results will be compared with traditional sensory and motor block assessments to determine whether PI provides an earlier and objective assessment of block success.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07507227
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
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Other University of Gaziantep trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07507227 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Gaziantep
- Last refreshed: 2 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07507227.
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