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NCT07504614
Pre-etched Bioactive Versus Resin- Based Fissure Sealant for Permanent Molars Affected With Molar Incisor Hypomineralization (MIH): a Randomized Clinical Trial
NA trial testing Pre-etched Bioactive Sealant in Molar Incisor Hypomineralization in 76 participants. Enrolling by invitation.
30 August 2027
Quick facts
| Lead sponsor | Jordan University of Science and Technology |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 76 |
| Start date | 1 August 2025 |
| Primary completion | 30 August 2027 |
| Estimated completion | 30 August 2027 |
| Sites | 1 location across Jordan |
Drugs / interventions tested
- Pre-etched Bioactive Sealant
- Conventional Resin-based Sealant
Conditions studied
- Molar Incisor Hypomineralization — all drugs for Molar Incisor Hypomineralization →
- Fissure Sealant — all drugs for Fissure Sealant →
Sponsor
Jordan University of Science and Technology
Who can join
Adults 6 to 12, any sex, with Molar Incisor Hypomineralization or Fissure Sealant. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to evaluate and compare the clinical performance of pre-etched bioactive fissure sealants to conventional RBFS in permanent molars affected by MIH in terms of retention, marginal integrity, caries prevention effect, and sensitivity.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07504614
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Molar Incisor Hypomineralization
Currently open trials in the same condition.
- NCT07389148 — Salivary Cortisol Levels in Children With Molar Incisor Hypomineralization · recruiting
- NCT07469124 — Clinical Evaluation of Resin Infiltration Treatment of MIH-affected Teeth in Pediatric Patients · NA · active not recruiting
- NCT07352813 — Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children · NA · recruiting
- NCT06776471 — Clinical Evaluation of Two Different Pit and Fissure Sealants · NA · recruiting
- NCT06362681 — Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study · NA · recruiting
Other Jordan University of Science and Technology trials
Trials by the same sponsor.
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- NCT07318298 — Effect of Injectable Hyaluronic Acid (HYADENT BG (HA)) on Bone Healing in Extraction Sockets · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07504614 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jordan University of Science and Technology
- Last refreshed: 1 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07504614.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing