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NCT07389148
Salivary Cortisol Levels in Children With Molar Incisor Hypomineralization
trial in Molar Incisor Hypomineralization in 90 participants. Currently enrolling.
26 March 2026
Quick facts
| Lead sponsor | Lokman Hekim University |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 90 |
| Start date | 26 January 2026 |
| Primary completion | 26 March 2026 |
| Estimated completion | 26 April 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Molar Incisor Hypomineralization — all drugs for Molar Incisor Hypomineralization →
Sponsor
Lokman Hekim University
Who can join
Adults 8 to 12, any sex, with Molar Incisor Hypomineralization. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Molar incisor hypomineralization (MIH) is a developmental condition that affects the enamel of permanent molars and incisors in children and may cause tooth sensitivity, discomfort, and difficulties during dental treatment. These problems can increase dental anxiety and lead to physiological stress responses during dental visits. The purpose of this observational study is to evaluate physiological stress responses in children with MIH by measuring salivary cortisol levels, heart rate, and oxygen saturation, and to compare these findings with those of children without MIH. A total of 90 children aged 8 to 12 years will participate in the study, including 45 children diagnosed with MIH and 45 healthy control participants. Participation involves no treatment or intervention beyond a routine clinical dental examination. Heart rate and oxygen saturation will be measured during the dental visit, and saliva samples will be collected immediately after the examination using a non-invasive method to assess cortisol levels. The results of this study may contribute to a better understanding of stress responses in children with MIH and support the development of more individualized and anxiety-sensitive dental care approaches.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07389148
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Related trials
Other recruiting trials for Molar Incisor Hypomineralization
Currently open trials in the same condition.
- NCT07469124 — Clinical Evaluation of Resin Infiltration Treatment of MIH-affected Teeth in Pediatric Patients · NA · active not recruiting
- NCT07352813 — Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children · NA · recruiting
- NCT06776471 — Clinical Evaluation of Two Different Pit and Fissure Sealants · NA · recruiting
- NCT06362681 — Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study · NA · recruiting
- NCT05964387 — Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars · NA · recruiting
Other Lokman Hekim University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07389148 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Lokman Hekim University
- Last refreshed: 9 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07389148.
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