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NCT07504250: HAM-DCR
Hyaluronic Acid vs Mitomycin-C in External Dacryocystorhinostomy
Phase 4 trial testing Hyaluronic Acid (HA) in Dacryocystitis in 36 participants. Not yet recruiting.
30 October 2027
Quick facts
| Lead sponsor | All India Institute of Medical Sciences, Bhubaneswar |
|---|---|
| Phase | Phase 4 |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 36 |
| Start date | 1 April 2026 |
| Primary completion | 30 October 2027 |
| Estimated completion | 31 December 2027 |
Drugs / interventions tested
- Hyaluronic Acid (HA) — full drug profile →
- Mitomycin -C
Conditions studied
- Dacryocystitis — all drugs for Dacryocystitis →
Sponsor
All India Institute of Medical Sciences, Bhubaneswar
Who can join
Adults 18 to 65, any sex, with Dacryocystitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
RCT to compare the surgical success in patients undergoing external dacryocystorhinostomy with intraoperative Mitomycin-C (0.4 mg/ml) Vs Hyaluronic acid 1% (1ml) as adjuvant, To compare the complication rates and wound healing patterns in each group, To Compare change in tear MMP-9 levels from preoperative (within 1 week before surgery) to postoperative (6 weeks after surgery) , To compare the comfort levels of patients in each group.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07504250
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07504250 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by All India Institute of Medical Sciences, Bhubaneswar
- Last refreshed: 31 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07504250.
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