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NCT07498504

RECOVER-Adult Cycle 2: A Long-Term Follow Up Study of Post-Acute Sequelae of SARS-CoV-2 Infection in Adults

Not yet recruiting Last updated 23 March 2026
What this trial tests

trial in Long COVID in 5,205 participants. Not yet recruiting.

Timeline
1 May 2026
Primary endpoint
1 April 2030
1 April 2030

Quick facts

Lead sponsorNYU Langone Health
StatusNot yet recruiting
Study typeOBSERVATIONAL
Enrollment5,205
Start date1 May 2026
Primary completion1 April 2030
Estimated completion1 April 2030
Sites1 location across United States

Conditions studied

Sponsor

NYU Langone Health — full company profile →

Who can join

Adults 18 to 100, any sex, with Long COVID or Long Covid19. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Sponsor's own description

Long COVID (LC) affects an estimated 5-10% of individuals with SARS-CoV-2 causing a persistent physical, cognitive, and functional impairment with potentially severe socioeconomic consequences. While RECOVER-Adult cycle 1 established the largest, most comprehensive U.S. adult LC cohort (14,730 participants), key questions remain about long-term disease trajectories, biological mechanisms, and late-emerging complications. RECOVER-Adult cycle 2 will follow selected participants for two years each, focusing on neurocognitive, cardiopulmonary and infection-associated chronic conditions (IACC) such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and autonomic dysfunction. Using a case-cohort design, the study will investigate disease persistence versus resolution, biological mechanisms, and onset of new chronic illnesses, generating critical insights to guide prevention, treatment, and public health policy.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Long COVID

Currently open trials in the same condition.

Other NYU Langone Health trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07498504.

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